This work aimed to prepare a nanoemulsion preparation containing budesonide and assess its aerodynamic behavior in comparison with suspension of budesonide. In-vitro aerodynamic performance of the corresponding micellar solution (ie. nanoemulsion preparation without oil) was investigated too. Nanoemulsions of almond oil containing budesonide, as a hydrophobic model drug molecule, were prepared ...

Adjustments to cricothyroid and thyroarytenoid muscle activation are critical to the control of fundamental frequency and aerodynamic aspects of vocal fold vibration in humans. The aerodynamic and physical effects of these muscles are not well understood and are difficult to study in vivo. Knowledge of the contributions of these two muscles is essential to understanding both normal and disorder...

The flight profile of typical small unmanned air systems (UAS) has expanded in the last decade beyond those encountered by traditional fixed-wing transport and rotary-wing aircraft. These new flight conditions may involve unusual flight mechanics as with flapping wing flight or complex aerodynamics when performing difficult maneuvers as part of routine operations. Such scenarios typically invol...

Unanticipated and unknown changes in an aircraft’s aerodynamic stability derivatives may cause undesirable effects that render pre-designed control laws unsuitable for maintaining stability. Gradual changes in the stability derivatives may be due to icing on lifting surfaces, whereas structural damage may cause a sudden change. For this study, we use the nonlinear NASA Generic Transport Model (...

Abstract: This paper reports about progress in the development of numerical tools for adaptive aerodynamic configuration design. We try to illustrate the use of new software components allowing for the parameterized modelling of boundary conditions and the simulation of compressible steady and unsteady viscous flows including a computational flow control model. A coupling of these tools and the...

This paper documents recent advances towards an efficient computational method for accurately determining the static and dynamic stability and control (S&C) characteristics of high-performance aircraft and demonstrates how it may fit into the SEEK EAGLE Store Certification Process;. In contrast to the “brute force” approach to filling an entire S&C database for an aircraft, the present approach...

The recent development of the world’s rst robotic insect capable of vertical takeo at the Harvard Microrobotics Lab has sparked research e orts into devising similar vehicles capable of untethered ight. The vehicle design has been extended in simulation to use one actuator per wing to produce sinusoidal apping motion in a plane. This work proposes employing a generic triangular wave to generate...