Cationization of BSA generates a molecule that mounts antibody responses of increased magnitude and duration and induces T cell proliferation at concentrations 500 times less than native BSA (nBSA). To explain the alteration in immunogenic properties of this Ag, the uptake of nBSA and cationized BSA (cBSA) by splenic APC has been investigated. T cell proliferation assays were conducted with nBS...

The JAK-STAT pathway is activated in the early and late phases of ischemic preconditioning (IPC) in normal myocardium. The role of this pathway and the efficacy of IPC in hypertrophied hearts remain largely unknown. We hypothesized that phosphorylated STAT-3 (pSTAT-3) is necessary for effective IPC in pressure-overload hypertrophy. Male Sprague-Dawley rats 8 wk after thoracic aortic constrictio...

Tuberculous meningitis (TBM) is the most common form of chronic infection of the central nervous system. Despite the magnitude of the problem, the general diagnostic outlook is discouraging. Specifically, there is no generally accepted early confirmative diagnosis protocol available for TBM. Various Mycobacterium tuberculosis antigens are now recognized as potential markers for diagnosis of TBM...

Mosquito repellent plants are used in the rural areas of Zimbabwe despite the fact that very few of them have been biologically evaluated. Leaves of the plant Lippia javanica, were collected from Mumurwi village, Zimbabwe and evaluated for repellency against laboratory reared Aedes aegypti mosquitoes. Major plant compounds were identified using Thin Layer Chromatography (TLC) and Mass Spectrome...

We present an interactive color g raphic system designed for pickup and delivery route modification . We identify three fundamental t y pes of commands and show that they correspond to those of a typical text editor. Nous presentons un systeme graphique avec un ec ran couleur pour ef fec tuer la modification de parcours de vehicules de transpor t. Nous identifions trois types fond amentaux de c...

BACKGROUND Direct smear examination with Ziehl-Neelsen (ZN) staining for the diagnosis of pulmonary tuberculosis (PTB) is cheap and easy to use, but its low sensitivity is a major drawback, particularly in HIV seropositive patients. As such, new tools for laboratory diagnosis are urgently needed to improve the case detection rate, especially in regions with a high prevalence of TB and HIV. OB...