BACKGROUND The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. OBJECTIVE The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. METHODS Oral smears were collected from clinically normal-appearing buccal mucosa ...

Objectives: To compare the different histological variants of ameloblastoma in terms of proliferative activity, using the histochemical method of AgNORs and to grade different variants of ameloblastoma. Methods: It was a cross sectional study of 50 surgical specimens, collected by non probability convenient sampling technique, of ameloblastoma were selected from different hospitals of Lahore (M...

AIM To determine the potential value of interphase cytogenetic and argyrophilic nucleolar organiser region (AgNOR) analyses in the diagnosis and classification of hydatidiform moles. METHODS Serial tissue sections from 37 hydatidiform moles, histologically classified as 11 complete and 15 partial, and from 11 hydropic abortuses were examined by in situ hybridisation using digoxigenin labelled...

BACKGROUND In conventional cytological diagnosis of pleural effusions the assessment of morphological features plays an important part. However, false negative and false positive results may occur. In this study conventional cytology was compared with flow cytometric DNA analysis and the argyrophil staining technique for nucleolar organiser regions (AgNOR) to characterise benign and malignant e...

BACKGROUND Proliferative potential of testicular tumor was assessed by immunohistochemistry using anti-proliferating cell nuclear antigen (PCNA) monoclonal antibody and silver staining of argyrophilic nucleolar organizer region (AgNOR), and the results were compared with clinical course. METHODS Fourty-five patients with testicular tumor and 10 normal testicles were investigated. All specimen...

AIM To investigate the prognostic significance of DNA ploidy and silver stained nucleolar organizer regions (AgNOR), as well as their relation to the histological grade and Dukes' stages of colorectal carcinomas, and the relation of tumor cells proportion in the S-phase and Dukes' stage, histologic grade, DNA ploidy, or AgNOR count. METHODS DNA flow cytometric analysis and AgNOR were performe...

In the first cytogenetic study of the recently proposed family Myerslopiidae the male karyotype of Mapucheachilensis (Nielson, 1996) was analyzed using conventional chromosome staining, AgNOR- and C-bandings, and fluorescence in situ hybridization (FISH) with 18S rDNA and (TTAGG) n telomeric probes. A karyotype of 2n = 16 + XY, NOR on a medium-sized pair of autosomes, subterminal location of C-...

Aim. The aim of the paper was to evaluate AgNOR parameters for discrimination benign from malignant breast tumors via a new approach - total area/nuclear area (TAA/NA). Material and methods. Three groups, consisting control (n = 14), 18) 28) participants were included in study. staining technique performed both mean number TAA/NA ratio evaluated. Results. While differences between patient group...