نتایج جستجو برای: air microenvironment

تعداد نتایج: 233751  

Abasalt Hosseinzadeh Colagar Mohammad Reza Hashemzadeh Mohammad Reza Jaafari Zahra Seyedi

Background Recent studies revealed that tumor-associated macrophages (TAMs) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis and immune functions within tumor microenvironments. Signal transducer and activator of transcription 3 (STAT3), which is a point of convergence for numerous oncogenic signalling pathways, is constitutively activ...

Introduction: Introduction: Molecular components within the microenvironment act upon cell growth, survival/apoptosis, and proliferation. Immune system cells respond to molecules produced by the tumor and released in the surrounding microenvironment, such as cytokines, chemokines, and growth factors. This study aimed to identify the effects of tumor environment on monocyte-macrophage cell linea...

2012
Payam Dadvand Audrey de Nazelle Margarita Triguero-Mas Anna Schembari Marta Cirach Elmira Amoly Francesc Figueras Xavier Basagaña Bart Ostro Mark Nieuwenhuijsen

BACKGROUND Green spaces are reported to improve health status, including beneficial effects on pregnancy outcomes. Despite the suggestions of air pollution-related health benefits of green spaces, there is no available evidence on the impact of greenness on personal exposure to air pollution. OBJECTIVES We investigated the association between surrounding greenness and personal exposure to air...

Journal: :International Journal of Cancer 2007

2013
Michael H Kershaw Christel Devaud Liza B John Jennifer A Westwood Phillip K Darcy

The tumor microenvironment is a complex assortment of cells that includes a variety of leukocytes. The overall effect of the microenvironment is to support the growth of tumors and suppress immune responses. Immunotherapy is a highly promising form of cancer treatment, but its efficacy can be severely compromised by an immunosuppressive tumor microenvironment. Chemotherapy and radiation treatme...

2017
Patrick C. Sachs Peter A. Mollica Robert D. Bruno

The accumulated evidence points to the microenvironment as the primary mediator of cellular fate determination. Comprised of parenchymal cells, stromal cells, structural extracellular matrix proteins, and signaling molecules, the microenvironment is a complex and synergistic edifice that varies tissue to tissue. Furthermore, it has become increasingly clear that the microenvironment plays cruci...

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