The adverse effects and treatment failures to some of the currently recommended drugs for giardia infection have given rise to the need for alternative antigiardial agents. In an open, randomized parallel group study, the safety and efficacy of albendazole was compared with that of metronidazole for the treatment of giardiasis in children. Sixty two children aged between 2-12 years were randomi...

PURPOSE To describe the evolution of a series of cases of diffuse unilateral subacute neuroretinitis (DUSN) treated with albendazole. METHODS Interventional case series. The authors developed a non-randomized clinical trial protocol to investigate the clinical evolution of diffuse unilateral subacute neuroretinitis cases treated with albendazole. According to protocol criteria up to now, six ...

We present a case of ocular toxocariasis treated successfully with oral albendazole in combination with steroids. A 26-year-old male visited the authors' clinic with the chief complaint of flying flies in his right eye. The fundus photograph showed a whitish epiretinal scar, and the fluorescein angiography revealed a hypofluorescein lesion of the scar and late leakage at the margin. An elevated...

in current study, a few sheep cystic livers and lungs were obtained from mashhad slaughter house and protoscolex were separated aseptically. thirty 6-week-old swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. in group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

abstract strongyloidiasis is caused by infestation with strongyloides stercoralis, a free living tropical and semitropical soil helminth that has a larval form that penetrates intact skin. clinical manifestations may be varied from an asymptomatic infection in immunocompetent hosts to a diffuse and fatal form in immunocompromised hosts. we report a 56-year-old man from dezful (south-west of ira...

The main objectives of this study were (a) to evaluate the in vitro performance of the rapid disintegration tablets as a way to improve the solid dispersions and (b) to study the in vivo pharmacokinetics of the albendazole modified formulation in dogs. Rapid disintegration of tablets seems to be a key factor for efficiency of solid dispersions with regard to improvement of the albendazole bioav...

BACKGROUND Metronidazole is the most commonly used drug for the treatment of giardiasis in humans. In spite of its therapeutic efficacy for giardiasis, low patient compliance, especially in children, side effects, and the emergence of metronidazole-resistant strains may restrict its use. Albendazole has been used to treat Giardia duodenalis infections in recent years. However, efficacy studies ...

BACKGROUND & OBJECTIVE Albendazole, a commonly used anthelminthic drug that targets the polymerization of alpha- and beta-tubulin dimer is currently co-administered with the antifilarial drug, diethylcarbamazine citrate (DEC) in the ongoing Global Programme for Elimination of Lymphatic Filariasis (GPELF). The experience in veterinary field has shown that there can be a rapid development of resi...

Formulations of poorly aqueous soluble drugs in different polymers based on solid dispersion method have been used to improve its solubility and drug bioavailability. The aim this study was formulate albendazole utilising cellulose obtained from saccharum officinarum pseudostem bagasse characterised. Herein, a 32 factorial design factor out 9 combinations the generated (GC) lactose. In each cas...