OBJECTIVE To evaluate the hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rats. METHODS Hypoglycemic activity of Brassica juncea (seeds) aqueous extract at a dose of 250, 350 and 450 mg/kg body weight was evaluated. Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated. RESULTS The serum insulin levels ...

The effects of administration of aqueous extract of Alchornea laxiflora leaf at doses of 100, 200 and 300 mg/kg body weight on some antioxidant enzymes and lipid peroxidation in iron deficient albino rats were investigated. Thirty six albino rats (51.17±1.02g) were used for the study. Eight rats were fed on iron-sufficient diet while the remaining twenty eight were made iron-deficient by mainta...

Objective: To find out the effect of Shilajit on lipid profile of hyperlipidemic albino rats and comparison with simvastatin. Study design: It is a case-controlled interventional study of eight weeks’ duration. 30 adult male albino rats weighing about 220-250g divided randomly into three groups A, B, and C. Hyperlipidemia was induced in B and C; afterwards drugs, Shilajit and simvastatin were g...

The present study was conducted to evaluate the hepatoprotective effects of an aqueous leaf extract of Coccinia grandis on carbon tetrachloride (CCl4) induced liver damage in albino rats. Wistar albino rats weighing around 180-200g were used. Toxicity was induced by using 30% CCl4 suspended in olive oil (1.0 ml/kg body wt intraperitoneal) after every 72 hrs for 3doses. The aqueous leaf extract ...

PURPOSE To investigate the capacity of mature retinal pigment epithelium (RPE) cells to enter the cell cycle in vivo using a range of RPE-specific and proliferative specific markers in both pigmented and albino rats. METHODS Whole-mounted retinas of both Dark Agouti and albino rats were immunolabeled with cell cycle markers Ki67 or PCNA and double labeled with RPE cell marker RPE65 or CRALBP....

Air pollution is the most serious environmental issue and becoming a threat to all over the world. SO2 is considered as one of the most poisonous and irritant gas because it alters the physiology, biochemistry and behavior of the living individuals. The present study has been conducted to demonstrate the remedial effect of Emblica officinalis against SO2 induced hepatotoxicity in albino rats. T...

Abstract Objectives The number of studies examining the circulating level change betatrophin and cartonectin in metabolic syndrome applying different loads exercise is limited. purpose present study was to investigate how exercises regulate levels induced rats. Methods A total 24 Wistar-Albino male rats were used study. Rats divided into four groups as follows; G1: control group (fed with stand...

correspondence: Erhabor Osaro Blood sciences Department, Royal Bolton hospital, Bolton Lancashire, UK Tel +44 79 3236 3217 Email [email protected] Abstract: This study was carried out to investigate the effect of prolonged intake of calciumchannel blocker amlodipine, an antihypertensive drug on gonadal steroid hormone (testosterone) of male albino rats. Three different concentrations of amlodip...

Albinism in mammals is accompanied by specific morphological and functional alterations of the visual system. To understand their cellular basis we studied the physiological characteristics and transmembrane currents of pyramidal neurons in 350-microm-thick slices of visual cortex from pigmented and albino rats using whole-cell and gramicidin perforated patch-clamp recordings. The resting membr...

Objective: In this study we investigated the effect of Fluoxetine, a selective serotonin reuptake inhibitor, on the gravimetry, hematology and whole brain histopathology in the restrained stressed male albino rats. Methodology: Adult male Wistar albino rats weighing about 175-225 g were taken for the study and were divided into four groups of six animals each. Group I (control), Group II (stres...