A synthetic route developed for the preparation of the A-ring of Taxol family of molecules is reported. By means of an intramolecular Diels-Alder reaction an asymmetric approach to this ring has been accomplished. Also, initial studies to prepare the A ring using an intramolecular Diels-Alder reaction have been successful.

Author details Department of Biostatistics, The University of Liverpool, Liverpool L69 3BX, UK. Alder Hey Children’s NHS FT, East Prescott Road, Liverpool L12 2AP, UK. Professor in Paediatric Endocrinology & Honorary Consultant, Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. Department of Biochemistry, Alder Hey Children’s NHS FT, East...

Plant species establishment and survival along environmental gradients have commonly been attributed to different environmental niches, life-history and adaptive traits [1]. Effective phenotype adaptation of alder species to extreme soil conditions allows them to form canopy-closed forest vegetation on alluvial and marshland localities. Alder forests represent azonal plant communities developed...

Herein we disclose the radical cation Diels–Alder reaction of aryl vinyl ethers by electrocatalysis, which is triggered by an oxidative SET process. The reaction clearly proceeds in a stepwise fashion, which is a rare mechanism in this class. We also found that two distinctive pathways, including “direct” and “indirect”, are possible to construct the Diels–Alder adduct. Introduction Umpolung, a...

Dimeric forms of norbornadiene and benzonorbornadiene were synthesized starting with known monobromide derivatives. The Diels-Alder cycloaddition reaction of dimers with TCNE and PTAD was investigated and new norbornenoid polycyclics were obtained. All compounds were characterized properly using NMR spectroscopy.

the effect of european black alder (alnus glutinosa l.) on the contents of carbon and nitrogen,exchangeable base cations, and plant available forms of phosphorus in the reclaimed mine soils formed bywaste deposition from opencast lignite mines was researched in central serbia. it was concluded that thegreatest part of dead organic residues reaching the soil under european black alder monocultur...

A novel and convenient approach, the domino retro Diels-Alder/Diels-Alder reaction sequence for highly stereo- and regioselective synthesis of various bicyclo[2.2.2]octenone and bicyclo[2.2.2]octadienone derivatives is presented. Thus, the masked o-benzoquinones (MOBs) 2a-e generated by the pyrolysis of the respective dimers 3a-e participated in this novel synthetic strategy with a variety of o...