The effect of chemical mutagens on the induction of mitotic chromosomal aberrations in diploid Allium cepa and tetraploid Allium vineale has been studied. In inducing chromosomal aberrations in case of both diploid and tetraploid Allium all the mutagens were found to be effective . Mitotic irregularities were higher in tetraploid species as compared with the diploid species. All types of chemic...

The influence of a permitted yellow food colour, Sunset yellow –FCF on root tips of Allium sativum was investigated with a view to ascertaining its mitodepressive effect. Root tips of Allium sativum were treated with five concentrations of Sunset yellow like 100 ppm,250 ppm,500 ppm,750 ppm and 1000 ppm and with distilled water as control. The time of action of the respective concentration of so...

The effect of aqueous extract of Allium sativum on phospatases activity in albino rats was investigated. Twelve rats were randomly grouped into four where rats in B, C and D groups were treated daily with oral administration of aqueous extract of Allium sativum at 50mg/kg, 100mg/kg and 150mg/kg body weight respectively for two weeks. The control group A received no treatment. The results showed...

Plants of the Allium genus, for example garlic and onion, are relatively odourless as long as they are intact. But if they are crushed or cut, a bunch of strong aromas are released. This is the result of a reaction between the enzyme alliinase and its substrates, alk(en)yl cysteine derivatives, probably as a defence against pests (Ellmore et al., 1994; Ankri et al., 1999). This occurs after cel...

Allium vegetables have been employed for a long time in traditional medical practice to treat a variety of diseases. Onion (Allium cepa L.), one of the representative Allium vegetables, has been used for centuries for its pungency, flavoring value, and medicinal properties. The bulb of onion is used medicinally and has been consumed as seasoning food for many centuries (Sengupta et al., 2004). ...

Antimicrobial activity of different concentrations (50, 100, 200, 300 and 500ml/l) of essential oil extracts of three type of onions (green, yellow and red) and garlic against two bacteria, Staphylococcus aureus, Salmomella Enteritidis, and three fungi, Aspergillus niger, Penicillium cyclopium and Fusarium oxysporum, was investigated. The essential oil (EO) extracts of these Allium plants (garl...

This review highlights the pharmacology, pharmacokinetics, pharmacological actions, therapeutic uses and adverse effects of cannabinoids. The effect of cannabinoids on anaesthesia is mentioned briefly. Important advances have taken place in cannabinoid research over the last few years and have led to the discovery of novel ligands. The possible clinical applications of these ligands and the dir...

Clinical application of evidence-based pharmacogenomics information has the potential to help healthcare professionals provide safe and effective medication management to patients. However, there is a gap between the advances of pharmacogenomics discovery and the health professionals' knowledge regarding pharmacogenomics testing and therapeutic uses. Furthermore, pharmacogenomics education mate...

To screen the wound healing activity of different extracts of Allium cepa L. in excision, incision and dead space wound models in albino rats. The tubers of Allium cepa L. (Family Liliaceae) were exhaustively defatted with petroleum ether (40-60C) and the marc was subjected to continuous extraction with solvent ether, chloroform, alcohol and chloroform water I.P. All the extracts were tested fo...