More than 140 million people dwell at altitudes of over 2500 m. The Andes region is home to the greatest population density at an altitude of more than 3500 m. Equally, the number of persons living at sea level (SL) is growing, and they travel to medium, high, or extreme altitudes for occupational or scientific reasons, or to enjoy tourism or recreational activities, as is the case of hikers, m...

OBJECTIVE Physical activity is important for well-being but can be challenging for people with diabetes. Data informing support of specialist activities such as climbing and high-altitude trekking are limited. A 42-year-old man with type 1 diabetes (duration 30 years) attended a Multidisciplinary Physical Activity and Diabetes Clinic planning to climb Mont Blanc during the summer and trek to Ev...

Peribronchial edema has been proposed as a mechanism enhancing airway responses to constrictor stimuli. Acute exposure to altitude in nonacclimatized lowlanders leads to subclinical interstitial pulmonary edema that lasts for several days after ascent, as suggested by changes in lung mechanics. We, therefore, investigated whether changes in lung mechanics consistent with fluid accumulation at h...

INTRODUCTION Intracerebral hemorrhage (ICH) at high altitude is not well understood to date. This study investigates the effects of high altitude on ICH, and examines the acute neuroprotection of hyperbaric oxygen (HBO) therapy against high-altitude ICH. METHODS Minipigs were placed in a hypobaric chamber for 72 h before the operation. ICH was induced by an infusion of autologous arterial blo...

yarrow (achillea spp.) belonging to the family of asteraceae with useful properties, such as anti-diaphoretic, anti-hemorrhagic, anti-inflammation, anti-biotic, anti-fungal, anti-bacterial, carminative and anti-oxidant effects. the present investigation assessed the morphological diversity of achillea aucheri, which is indigenous plant from damavand mountain of iran. the samples were collected ...

Yarrow (Achillea spp.) belonging to the family of Asteraceae with useful properties, such as anti-diaphoretic, anti-hemorrhagic, anti-inflammation, anti-biotic, anti-fungal, anti-bacterial, Carminative and anti-oxidant effects. The present investigation assessed the morphological diversity of Achillea aucheri, which is indigenous plant from Damavand mountain of Iran. The samples were collected ...

BACKGROUND Cognitive impairment is common in people travelling to high altitude. Oxiracetam and electrical stimulation of cerebellar fastigial nucleus may have beneficial impacts. This study was to investigate the effects of preconditioning with Oxiracetam or fastigial nucleus stimulation (FNS) on cognitive decline following the ascension to high altitude. METHODS The study was conducted on 6...

There are only a few conflicting reports on the effects of moderate altitude on cognitive factors that could affect sporting performance. An investigation of choice reaction time in international rugby players at various altitudes was therefore carried out. The results suggest that moderate altitude has no significant effect on this parameter in highly trained competitive athletes.

contributions of peripheral muscle fatigue to exercise performance. neurological changes after a single high altitude climb. Med Sci Sports Exerc 31:969–972. mineral density: a twin study. et al. 1997. The effects of high altitude trekking on body composition and resting metabolic rate.

BACKGROUND Pulmonary hypertension is a hallmark of high-altitude pulmonary edema and may contribute to its pathogenesis. When administered by inhalation, nitric oxide, an endothelium-derived relaxing factor, attenuates the pulmonary vasoconstriction produced by short-term hypoxia. METHODS We studied the effects of inhaled nitric oxide on pulmonary-artery pressure and arterial oxygenation in 1...