نتایج جستجو برای: alzheimer disease ad
تعداد نتایج: 1556084 فیلتر نتایج به سال:
Commentary My standard epilepsy talk for medical students used to include the following: The incidence of epilepsy has a bimodal distribution , and the causes of epilepsy in children are different from those in older adults. New-onset epilepsy in the elderly is often a consequence of accumulated injuries to the brain, including from stroke, brain tumors, and neurodegenerative diseases. Although...
Age is the major risk factor for Alzheimer disease (AD) but age confounds biological aging with elapsed time. Non-human animals do not spontaneously develop Alzheimer disease (AD) as they age and transgenic mouse models of AD can only model some aspects of the earliest portion of the pre-clinical phase of AD. Transgenic models do not produce substantial neuron and synapse loss and consequently ...
Introduction: Previous studies have shown that exercise enhances cognitive and functional capacities in patients with Alzheimer's disease (AD). In this study, we investigated the effect of long-term (60 days) and shortterm (10 days) exercise on the spatial memory deficits in an animal model of AD. Methods: Fifty male rats were divided into 5 groups; 1) intact, 2) sham, 3) sham-Alzheimer 4) Alzh...
Clinical studies in the past have shown that the pathology of Alzheimer’s disease (AD) initiates, 10 to 15 years before the visible clinical symptoms of cognitive impairment starts to appear in AD diagnosed patients. Therefore, early diagnosis of the AD using potential early stage cerebrospinal fluid (CSF) biomarkers will be valuable in designing a clinical trial and proper care of AD patients....
Non-steroidal anti-inflammatory drugs (NSAIDs) identified effective in many diseases. One of which is neurodegenerative diseases including Alzheimer disease (AD). In this study gross alteration of gene expression in AD mice by ibuprofen treatment is investigated via Protein-protein interaction network (PPI) analysis. Expression profiling of microarray dataset GSE67306 was retrieved from GEO dat...
background: alzheimer’s disease (ad) is a progressive neurodegenerative disease and nowadays the role of endothelial cell (ec) injury has been proposed in pathological process in ad. peroxisome proliferator‑activated receptor‑γ (ppar‑γ) agonist has anti‑inflammatory properties through activation in glial cells and improves vascular function and prevent atherosclerotic disease progression. the a...
because of the huge amounts of proteomic data and demand for new methods of laboratory analysis results, proteins collective analysis, in addition to taking less time, biostatistician assist at identification of new patterns in the data set. in this study, rat hippocampus proteome in normal and alzheimer's disease (ad) were analyzed by using proteomic techniques and bioinformatics’ analysis. pr...
The authors, a group of investigators with extensive research and clinical experience related to both late-life depression and Alzheimer disease (AD), propose provisional affective and behavioral inclusion and exclusion diagnostic criteria for Depression of AD.
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