despite development of new approaches for the treatment of cancer disease, it is the second cause of mortality in world. annually, 30000 persons die in iran due to cancer diseases. eighty percent of cancer patients are children which about 50% children lead to death. given the high rate of cancer-related death, the new approaches for prevention, control, early diagnosis, and treatment of this d...

Organic electrode materials have received increasing attention in rechargeable batteries due to their earth abundance and variable structures. However, the practical application of most organic is limited by high solubility electrolyte. Herein, an insoluble amino-functionalized hexaazatriphenylene (defined as HATN-[NH2]3) electrolyte developed stable cathode material for lithium-ion (LIBs). The...

Nanobodies can be seen as next-generation tools for the recognition and modulation of antigens that are inaccessible to conventional antibodies. Due to their compact structure and high stability, nanobodies see frequent usage in basic research, and their chemical functionalization opens the way towards promising diagnostic and therapeutic applications. In this Review, central aspects of nanobod...

The synthesis of benzylpenicilloyl-containing dendrimers has been achieved by a convenient procedure involving quantitative functionalization of the terminal amino groups of the three Starbust PAMAM generations used (G(n); n = 0, 1, 2). All these densely penicilloylated dendrimers (G(n)P) exhibit similar, simple NMR spectroscopic data suggesting highly symmetric structures and a monodisperse na...

High-performance poly(1,4-butylene terephthalate (PBT) nanocomposites have been developed via the consideration of phosphorus-containing agents and amino-carbon nanotube (A-CNT). One-pot functionalization method has been adopted to Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 17 January 2018 doi:10.20944/preprints201801.0161.v1 © 2018 by the author(s). Distributed under a Creativ...

The synthesis of 4-amino-3-cyano-N-arylpyrazoles A based on a Thorpe-Ziegler cyclization as the key step has been achieved using microwave activation. Via a new diversity-oriented synthetic pathway, these highly functionalized building blocks allowed the access to various heteroaromatic scaffolds such as pyrazolo-pyridines B, pyrazolo-pyrimidines C and pyrazolo-oxadiazoles D. Interestingly, the...

For the enantioselective diversification of a single starting material, different chiral catalyst is usually required for each transformation. Herein, we extend concept catalytically formed auxiliary from hydrogenation to asymmetric cyclopropanation and epoxidation tetra-substituted olefins, alleviating need catalysts in alkene functionalization step. The constructed propargylic amines Pd-catal...

Betulonic acid belongs to the pentacyclic triterpenic derivative class and can be obtained through the selective oxidation of betulin. In this study we set obtaining several functionalized derivatives of this compound by its condensation with several amino compounds such as aminoguanidine, hydroxylamine, n-butylamine and thiosemicarbazide as our goal. The functionalization of the parent compoun...

in this study, kinetics and mechanism of the sulfur dioxide adsorption on the single-walled carbon nanotubes (cnt) are investigated. three single-walled carbon nanotubes, including the armchair (6,6), chiral (6,5) and zigzag (6,0) cnts were chosen as the models and the different orientations of so2 molecule relative to the cnt axis were considered. the b3lyp functional within the 6-31g(d) basis...

Carboxylic acid-functionalized SWNTs prepared via the reaction of an amino acid, NH2(CH2)nCO2H, with fluoronanotubes show similar levels of sidewall functionalization; however, the solubility in water is controlled by the length of the hydrocarbon side chain (i.e., n). The 6-aminohexanoic acid derivative is soluble in aqueous solution (0.5 mg mL(-1)) between pH 4 and 11, whereas the glysine and...