A proposal unifying four approaches to genetic code is discussed. The first approach is introduced by myself and is geometric: genetic code is interpreted as an imbedding of the aminoacid space to DNA space possessing a fiber bundle like structure with DNAs coding for a given aminoacid forming a discrete fiber with a varying number of points. Also Khrennikov has proposed an analogous approach b...

This study aims to explore the ameliorative effects of L-glutamic acid (L-Glu) against carbon tetrachloride (CCl4) toxicity in male rats. Changes activities alanine and aspartate aminotransferases (ALAT, ASAT) were studied tissues blood Concentrations creatinine, triacylglycerol cholesterol also determined experimental animals. Intraperitoneal administration CCl4 rats led changes animals parame...

Crossreactivity of anti-HLA antibodies with SLA alleles may limit the use of pig xenografts in some highly sensitized patients. An understanding of the molecular basis for this crossreactivity may allow better selection of xenograft donors. We have tested 68 human monoclonal HLA class I antibodies (mAbs) for reactivity with pig lymphocytes from SLA defined pigs and found nine to be crossreactiv...

The present study demonstrates a new Millettia pinnata chalcone isomerase (MpCHI) whose transcription level in leaf was confirmed to be enhanced after being treated by seawater or NaCl (500 mM) via transcriptome sequencing and Real-Time Quantitative Reverse Transcription PCR (QRT-PCR) analyses. Its full length cDNA (666 bp) was obtained by 3'-end and 5'-end Rapid Amplification of cDNA Ends (RAC...

Microwave energy, at manually-adjusted, partial power settings has been used to hydrolyse bovine serum albumin at 125 degrees C. Hydrolysis was complete within 2 h, except for valine and isoleucine which were completely liberated within 4 h. The aminoacid destruction was less than that observed at similar hydrolysis conditions with other methods and complete hydrolysis was achieved more rapidly...

We have synthesised a novel oxanorbornene β-aminoacid derivative and employed it in a stereoselective Ugi reaction. Hypothesis regarding the mechanism taking place during the reaction have been made and validated through the determination of the relative and absolute configuration of the Ugi adducts. Use of the correct choice of solvents can increase stereoselection. The resulting bicyclic pept...

Heterogeneous bifuctional catalysts are multifunctional synthetic catalysts enabling efficient organic transformations by exploiting two opposite functionalities without mutual destruction. In this paper we report the first Er(III)-based metallorganic heterogeneous catalyst, synthesized by post-calcination MW-assisted grafting and modification of the natural aminoacid L-cysteine. The natural ac...

Starting with 35 grams of ethyl aminoacetate we recovered practically one-half of the aminoacid ester in the form of its hydrochloride, and obtained 19 grams of the isothiocyanacetate. This reaction isbeing investigated further and will be applied for the preparation of other new types of polyketide mustard oils. If this method of synthesis finds as wide an application as we anticipate, it will...