Knowledge of simulated genetic effects facilitates interpretation of methodological studies. Genetic interactions for common disorders are likely numerous and weak. Using the 200 replicates of the Genetic Analysis Workshop 16 (GAW16) Problem 3 simulated data, we compared the statistical power to detect weak gene-gene interactions using a haplotype-based test in the UNPHASED software with genoty...

The paper takes a close look at an emerging industry - decentralized finance on the blockchain. goal of this is to compare centralized order book (CLOB)-based exchanges automated market maker (AMM)-based (DEX) and analyze challenges that AMM-based DEXes are facing today using Uniswap as example.

This paper presents the dynamic modelling of a flexible robot manipulator incorporating payload. A planar flexible manipulator incorporating structural damping, hub inertia and payload that moves in the horizontal plane is considered. A dynamic model of the system is developed using a finite element and assumed mode methods (FEM and AMM). In this work will make a comparison between FEM and AMM....

In this study, we proposed a remote authentication model of information appliances (RAMIA). The RAMIA comprised of two basic components, namely user identity security authentication module (UISAM) and authority management module (AMM). The function of UISAM is to authenticate the user by account and password, this module is constructed by hash function and exclusive or (XOR);AMM includes a user...

Cyclic voltammetric surface waves were found for monolayers of Ru(bpy)Z(bpyY+, where bpy’ is 4-methyl4’-(dodecyl-l-thiol)-2,2’-bipyridine, which spontaneously adsorbs onto conducting substrates (indium tin oxide, polycrystalline gold). On polycrystalline gold, the monolayer, probably attached via the thiol functional group, is oxidized in an aqueous oxalate medium to produce electrogenerated ch...

Guidelines for ammonia toxicity in fish are often determined using static exposure tests with immature fish over a 96-h period. These results may not be relevant to aquaculture, hauling or angling tournament scenarios where mature fish can be exposed to ammonia for shorter durations, often following additional stressors such as handling. The current study sought to quantify (1) the impact of am...

Using a high-resolution ocean general circulation model forced by NCEP/NCAR reanalysis data, the interannual variability of the Guinea Dome is studied from a new viewpoint of its possible link with the Atlantic Meridional Mode (AMM), which is related to the meridional migration of the Intertropical Convergence Zone (ITCZ). The dome develops off Dakar seasonally from late spring to late fall owi...

This paper outlines a package synchronization scheme for blind speech watermarking in the discrete wavelet transform (DWT) domain. Following two-level DWT decomposition, watermark bits and synchronization codes are embedded within selected frames in the second-level approximation and detail subbands, respectively. The embedded synchronization code is used for frame alignment and as a location i...

Acute ammonia toxicity in vertebrates is thought to be characterized by a cascade of deleterious events resembling those associated with anoxic/ischemic injury in the central nervous system. A key event is the over-stimulation of neuronal N-methyl-D-aspartate (NMDA) receptors, which leads to excitotoxic cell death. The similarity between the responses to acute ammonia toxicity and anoxia sugges...

OBJECTIVE To determine if the type of antidepressant drug is related to adherence to National Committee for Quality Assurance (NCQA) Antidepressant Medication Management (AMM) quality measures and to assess the 6-month health care costs among newly diagnosed depressed patients. METHODS The MarketScan Commercial Claims and Encounter database for medical and pharmacy claims from January 2001 to...