background: coverage of the bronchial stumps (bss) with adjacent tissues can improve healing and reduce bronchial complications in complex thoracic surgery. there is no evidence for the application of human amnion allograft for prevention of air leak from the bs. the comparison of the amniotic membrane (am) and pleural patch for bs healing after lobectomy in dogs was our aim in this study. mate...

The region of the amnion overlying the placenta plays an active role in fluid exchange between amniotic fluid and fetal blood perfusing the surface of the placenta, whereas little transfer occurs across the reflected amnion that contacts the membranous chorion. Because aquaporins (AQPs) facilitate rapid movement of water across cells, we hypothesized that AQP gene expression in placental amnion...

The protective amniotic sac that is covering the foetus plays a very pivotal role in many aspects .The material which was once thought to be discarded during the delivery of the baby has now found immense applications for regeneration and revitalization of devitalized tissues. The amniotic membrane can be processed and the dehydrated amnion allograft can be used for ocular transplants, treatmen...

The relationship between Pre-eclampsia (PE) and placental production of Adrenomedullin (AdM) is not completely understood. This study measured placental and fetal membrane AdM protein concentrations by specific radioimmunoassay and mRNA expression by Northern blot analysis in samples obtained at either term or preterm gestation from women either in labour or not in labour. Samples were obtained...

Very high concentrations of prorenin protein occur in human amniotic fluid and amnion. The source of amniotic fluid prorenin is likely the decidua, as it has the highest levels of prorenin mRNA (REN). Conversely, REN mRNA levels in amnion and chorion are very low. This study aimed to investigate whether decidual prorenin could cross the amnion and accumulate in amniotic fluid. Late gestation am...

We demonstrated previously that preproendothelin mRNA is present in avascular human amnion tissue and in human amnion cells maintained in primary monolayer culture. In this investigation we sought to identify the specific endothelin (ET) gene that is expressed in amnion and to determine whether endothelin is produced by amnion. Using oligonucleotides specific for ET-1, ET-2, and ET-3 mRNA, we i...