We present a new method to analyze molecular and Brownian dynamics simulations of activated processes based on the concept of mean first-passage times. The new method provides a simple and efficient strategy to evaluate reaction rates and it facilitates the localization of the transition state directly from the kinetics of the system without the need of thermodynamical considerations. It also p...

One of the most difficult tasks in analyzing the results of the overall crystallization kinetics, controlled by the equation a 1⁄4 1 e Kt , is the determination of power n. Usually, this is done in double logarithmic coordinates, i.e. plotting ln[ In(1 a)] against ln t. Because of the property of the logarithmic function, ln0N, this method exaggerates the role of initial stages (a-0) as well as...

In the paper a new Multi-Layers approach (called MultiLayers Model MLM) for the analysis of stochastic signals and its application to the analysis of gene expression data is presented. It consists in the generation of sub-samples from the input signal by applying a threshold technique based on cut-set optimal conditions. The MLM has been applied on synthetic and real microarray data for the ide...

Article history: Received 20 January 2010 Available online 29 April 2010

BACKGROUND The Drosophila pupal eye has become a popular paradigm for understanding morphogenesis and tissue patterning. Correct rearrangement of cells between ommatidia is required to organize the ommatidial array across the eye field. This requires cell movement, cell death, changes to cell-cell adhesion, signaling and fate specification. METHODOLOGY We describe a method to quantitatively a...

Abstract The simultaneous measurement of the expression level of thousands of genes presents a real challenge to the information processing capability of the present computer systems and statistical software tools because of the complexity of the problems at hand and size of the data sets. These days research is concentrating on projects to find clusters in the biological samples and to identif...

This letter describes a method to analyze electromechanical stability of dielectric elastomer actuators. We write the free energy of an actuator using stretches and nominal electric displacement as generalized coordinates, and pre-stresses and voltage as control parameters. When the Hessian of the free-energy function ceases to be positive-definite, the actuator thins down drastically, often re...