The epithelial-mesenchymal transition (EMT) is a complex cancer progression that can boost the metastatic potential of transformed cells by inducing migration, loss of cell adhesion, and promoting proliferation under anchorage-independent conditions. A DNA microarray analysis was performed comparing parental anchorage-dependent MDCK cells and anchorage-independent MDCK cells that were engineere...

This study was conducted on a sample of thirty patients selected from Orthodontics department de’Montmorency College of dentistry/ Punjab dental Hospital, Lahore. The purpose of study was to evaluate treatment effects of Distal Jet Appliance during Class-II molar correction with a focus on the magnitude of Maxillary first molar distalization, its tipping, extrusion, rotation as well as anchorag...

An adult patient with proclination and spacing was performed orthodontic treatment combined with corticotomy and the burstone three piece intrusive arch who desired a shortened treatment period. The patient had Angle's Class I malocclusion with flaring of the maxillary and mandibular incisors. Pre adjusted edgewise appliance (MBT prescription) was fixed to the maxillary and mandibular teeth. Th...

Temporary Anchorage Devices have been the only means of providing absolute anchorage but complications causing soft and hard tissue damage requires well-formed cortical bone. Also, they are unable to tolerate torsional forces moments. For this reason, miniplates had come up with advantage more surface area difficult place as require flap surgery also removal post treatment. CTOR plates revoluti...

RANKL (receptor activator of NF-κB ligand) is a crucial cytokine for regulating diverse biological systems such as innate immunity, bone homeostasis and mammary gland differentiation, operating through activation of its cognate receptor RANK. In these normal physiological processes, RANKL signals through paracrine and/or heterotypic mechanisms where its expression and function is tightly contro...

A 16-year-old Class II female patient was treated without tooth extraction. The upper first molars were distalized by the Pendulum appliance. After six months, the molars tipped significantly to the distal. To correct this side effect, we decided to upright the molars using skeletal anchorage. On each side, a mini-screw was inserted between first and second premolars in the buccal cortical plat...

Abstract In this study, strand looseness in a multi-strand anchorage is identified using measured impedance features of the PZT (Lead zirconate titanate) interface array under temperature effects. Firstly, PZT-interface method for monitoring prestressed structures briefly described. Secondly, finite element model equipped with established to analyze effects prestress loss and changes features. ...

treatment method for dental Class II pa ­ tients with excessive overjet, anterior crowding, or both. Given the unpopularity of headgear among pa tients,1,2 clinicians increasingly prefer intraoral appliances with minimal need for patient coop­ eration. Unfortunately, most of the conventional non­compliance devices produce unwanted side effects. Anchorage loss of 24­55% can result in mesial migr...

Higher-functioning mitochondria that are more reduced and have less ROS are anchored in the yeast bud tip by the Dsl1-family protein Mmr1p. Here we report a role for mitochondrial fusion in bud-tip anchorage of mitochondria. Fluorescence loss in photobleaching (FLIP) and network analysis experiments revealed that mitochondria in large buds are a continuous reticulum that is physically distinct ...