Difluoromethylornithine (DFMO), a specific, irreversible, enzyme-activated inhibitor of ornithine decarboxylase activity, the first and rate-limiting step in polyamine biosynthesis, has been shown to inhibit neoplastic cell proliferation in culture. In most cases, such inhibition is not accompanied by cell loss, with the exception of multiple cell lines of human small cell lung carcinoma (SCC),...

The idea of absolute anchorage has always been an elusive goal for clinicians. Orthodontic mini-implants or temporary anchorage devices allow tooth movements previously thought to be impossible or difficult. Although extensive literature exists on use of temporary anchorage devices, their failures have been hardly focused upon, especially implant fracture. The following case report describes su...

with the growing population and density in metropolitan areas, higher tendency to live in high-rise buildings, and increasing demand for parking lots, it seems necessary to excavate soil to construct underground spaces. during excavation work, as the height of the wall increases, special care should be taken to the wall stabilization to avoid any consequent damage including extensive property d...

intra-oral appliances such as transpalatal arch and nance appliance fail to resist against forces that tend to loosen the anchorage. the infirmity arises due to the long lever arm and the mesial force that is perpendicular to the long axis of the appliance. the butterfly arch is presented here as an intra-oral appliance that withstands the mesially directed forces with a mechanism that puts str...

This study investigates the dynamic characteristics of a smart PZT interface mounted on prestressed anchorage to verify numerical feasibility admittance-based anchor force monitoring technique. Firstly, technique through single-mount is outlined. The admittance response interface-anchorage system theoretically derived show proof-of-concept for monitoring. Secondly, finite element model correspo...

Corrosion of orthodontic miniscrews or temporary anchorage devices (TADs) has been proposed as a contributor to inflammation, which in turn is a factor in the clinical success of miniscrews. The purpose of this study was to measure the electrochemical properties of orthodontic miniscrews in artificial saliva with and without fluoride. The corrosion properties of three miniscrew products (Vector...

GPI anchorage in the CEA family results in the acquisition of radically different functions relative to TM anchorage, including inhibition of differentiation and anoikis, disruption of tissue architecture and promotion of tumorigenicity. CEA GPI anchors, as determined by the carboxy-terminal exon of CEA, demonstrate biological specificity in their ability to confer these functional changes. CEA...

Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD). These devices are small, are implanted with a relatively...

OBJECTIVE The aim of this study was to evaluate the movement of impacted canines away from the roots of neighboring teeth before full-mouth bracket placement, performed by means of TADs to decrease undesired side effects on adjacent teeth. METHODS The study sample consisted of 34 palatally impacted canines, being 19 in the experimental group and 15 in the control group. In the experimental gr...

An ankylosed tooth can be suitable for obtaining orthodontic anchorage. However, if such a tooth lacks adequate clinical crown height, the anchorage will not be effective. In those situations surgical luxation or restorative crown augmentation is suggested. This case report is about the restorative treatment of an ankylosed, infraoccluded tooth to enhance the anchorage for forced orthodontic er...