Background and objectives: The role of genetic components in expression of proteins involved in signaling pathways of fat and carbohydrate metabolism has been well-demonstrated. The aim of this study was to determine effects of high intensity interval training (HIIT) on glucose, insulin, and insulin resistance levels as well as IRS1 expression in gastrocnemius muscle of obese Wistar rats. Meth...

Background: Obesity and insulin resistance refer to a clustering of various medical conditions, with a number of pathological components that contribute to the development of diabetes and cardiovascular disease. Some studies have shown that free testosterone levels are low in obese men and are inversely correlated with the degree of obesity. In addition, leptin levels increases with obesity tha...

results saffron extracts markedly (p < 0.05) decreased the serum total cholesterol (tc, 90 ± 9.3), triglyceride (tg, 99 ± 10.5), and low-density lipoprotein cholesterol (ldl-c, 27 ± 1.1) in obese rats, while they increased the serum high-density lipoprotein cholesterol (hdl-c, 68 ± 2.2). the atherosclerosis-index (ldl/hdl, 0.39 ± 0.5), atherogenic index (tc/hdl, 1.32 ± 4.2), and the liver enzym...

Obesity was associated with high serum vaspin concentrations and increased vaspin mRNA expression in human adipose tissue , insulin resistance, and type II diabetes. However, the mechanisms how vaspin secretion may be linked to deterioration of glucose metabolism and insulin sensitivity are not understood. The aim of this work is to explore the effect of dietary regimen for 6 months on serum va...

OBJECTIVE: Polycystic Ovary Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age characterized by the presence of polycystic ovaries, menstrual dysfunction and biochemical or clinical hyperandrogenism. Lifestyle modification is important in treatment of obese and overweight women with PCOS. This study was performed to evaluate the benefit of aerobic exercise training o...

objective: the aim of the present study is assessment of insulin resistance (ir) in obese women by tyg-index and compared with the homa-ir index. materials and methods: this cross-sectional study was performed on 61 obese women aged 18-45 years. weights, height, waist circumference (wc) were measured and body mass index (bmi) was calculated and recorded. a sample of fasting serum was collected ...

objective: polycystic ovary syndrome (pcos) is the most common endocrinopathy in women of reproductive age characterized by the presence of polycystic ovaries, menstrual dysfunction and biochemical or clinical hyperandrogenism. lifestyle modification is important in treatment of obese and overweight women with pcos. this study was performed to evaluate the benefit of aerobic exercise training o...