BACKGROUND The oriental river prawn, Macrobrachium nipponense, is an important aquaculture species in China, even in whole of Asia. The androgenic gland produces hormones that play crucial roles in sexual differentiation to maleness. This study is the first de novo M. nipponense transcriptome analysis using cDNA prepared from mRNA isolated from the androgenic gland. Illumina/Solexa was used for...

*Correspondence: Maria De Falco, Section of Evolutionary and Comparative Biology, Department of Biology, Via Mezzocannone, 8 80134 Naples, Italy e-mail: [email protected] Endocrine disrupting chemicals (EDCs) are identified for their ability to perturb the homeostasis of endocrine system and hormonal balance. The male reproductive system is under close control of hormones and each change in th...

The prevalence of cryptorchidism has increased over the past decades, yet its origins remain poorly understood. Testis descent is dependent on androgens and likely affected by endocrine disrupting compounds (EDCs), targeting androgen receptor (AR). We investigated association between anti-androgenic activity, not derived from natural hormones, in maternal breast milk impaired testis among boys....

Dehydroepiandrosterone (DHEA) hormones are the most abundant steroids in the human body. Low levels of DHEA are associated with aging and disease states. Specifically, a deficiency of DHEA has been found to correlate with immune dysfunction, inflammation, greater risk of certain cancers, heart disease in men, and osteoporosis. The special interest in DHEA replacement, however, stems from its fu...

Despite numerous studies reported during the past six years, the controversy concerning the effects of ACTH and cortisone on tuberculous infections continues. When one considers the many known and unknown factors that influence host-parasite relationships, the different reactions of different species to tuberculous infections, and the varied effects of different drugs and hormones on the infect...

A rapid gas chromatography-tandem mass spectrometry (GC-MS/MS) analytical method was developed for the simultaneous analysis of 7 estrogenic hormones (17α-estradiol, 17β-estradiol, estrone, mestranol, 17α-ethynylestradiol, levonorgestrel, estriol) and 5 androgenic hormones (testosterone, androsterone, etiocholanolone, dihydrotestosterone, androstenedione) in aqueous matrices. This method is uni...

In mammals, it is well established that circadian rhythms in physiology and behavior, including the rhythmic secretion of hormones, are regulated by a brain clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. While SCN regulation of gonadal hormone secretion has been amply studied, the mechanisms whereby steroid hormones affect circadian functions are less well known. This i...

© 1998 Journals of Reproduction and Fertility 1359-6004/98 $12.50 Steroid hormones play extremely important roles in maintaining bodily homeostasis and reproductive capacity. For example, the adrenal mineralocorticoid aldosterone is essential for maintaining salt balance and, hence, blood pressure, while adrenal glucocorticoids serve to regulate carbohydrate metabolism and also to formulate rea...