BACKGROUND Predilection of juvenile angiofibromas in adolescent boys has prompted the hypothesis of hormone-dependent tumor growth. However, knowledge on expression and function of sex hormone receptors in juvenile angiofibromas is still sparse and inconsistent. METHODS Transcript and protein expression of sex hormone receptors in juvenile angiofibromas was studied by quantitative reverse tra...

introduction: in recent years, the surgical management of angiofibroma has been greatly influenced by the use of endoscopic techniques. however, large tumors that extend into difficult anatomic sites present major challenges for management by either endoscopy or an open-surgery approach which needs new technique for the complete en block resection.   materials and methods: in a prospective obse...

BACKGROUND Postexcision residual disease in the vidian canal is speculated to contribute to recurrence in juvenile angiofibroma. METHODS We composed a prospective cohort of 16 consecutive patients with juvenile angiofibroma (stages IIA-IIIB). The presurgical vidian canal assessment was done by contrast-enhanced CT (1.2 mm collimation). At surgery after complete tumor excision, the vidian cana...

INTRODUCTION  Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and histologically benign tumor, generally observed in male adolescents. It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. Juvenile nasopharyngeal angiofibroma originates in the sphenopalatine forame, causing epistaxes and nasal obstruction. OBJECTIVE  To retrospec...

BACKGROUND Cellular angiofibroma represents a newly described, site specific tumor. Histologically, CAF is a benign mesenchymal neoplasm characterized by two principal components: bland spindle cells and prominent small to medium-sized vessels with mural hyalinization. The indolent nature of the lesion is underscored by the uniformity of its constituent stromal cells, and their lack of nuclear ...

INTRODUCTION In recent years, the surgical management of angiofibroma has been greatly influenced by the use of endoscopic techniques. However, large tumors that extend into difficult anatomic sites present major challenges for management by either endoscopy or an open-surgery approach which needs new technique for the complete en block resection. MATERIALS AND METHODS In a prospective observ...

Sinonasal and pharyngeal mass lesion of Extraskeletal Ewing sarcomas (EEWSs) are extremely rare. Herein we present a case EEWSs ethmoid sinus extending into nasal spaces mimicking as angiofibroma clinically. Histopathological examination in conjunction with immunohistochemistry puzzled out the diagnostic dilemma.

We present the case of a 9-year-old male patient, lacking morbid antecedents, referred to our service due to 2 episodes of massive epistaxis. The first one was selflimiting, while the second required anterior nasal packing. Physical examination revealed a tumour in the left nostril, with a vascularised appearance. The initial diagnosis was nasopharyngeal angiofibroma, due to the appearance of t...

BACKGROUND Cellular angiofibroma, first described in 1997, is known to occur in both genders with equal predilection occurring in middle aged females and older males. CASE PRESENTATION In this study, a case of vaginal cellular angiofibroma was reported in a 30 year old female presenting with secondary infertility. The case was diagnosed based on morphology and immunohistochemistry and was tre...