PURPOSE Coronary flow reserve (CFR) in the non-infarcted myocardium is often impaired following acute myocardial infarction (AMI). However, the clinical significance of CFR in the non-infarcted myocardium is not fully understood. The objective of the present study was to assess whether a relationship exists between CFR and left ventricular remodeling following AMI. MATERIALS AND METHODS We en...

An 81-year-old man with severe left ventricular dysfunction (left ventricular ejection fraction 24%), prior coronary artery bypass grafting, symptomatic heart failure (New York Heart Association class III), and an investigational percutaneously implanted permanent left atrial pressure (LAP) monitoring system (HeartPOD Savacor, Inc, Los Angeles, Calif) in situ (Figure 1) was admitted with an acu...

OBJECTIVES We sought to evaluate the importance of time in relation to treatment, time course and determinants of recovery of left ventricular (LV) function in patients with acute myocardial infarction (AMI) undergoing primary percutaneous transluminal coronary angioplasty (PTCA). BACKGROUND Myocardial salvage has been shown to be dependent on the time elapsed from the onset of AMI to reperfu...

Nineteen of 69 patients undergoing coronary angioplasty required immediate coronary surgery after the procedure. Six of these operations were planned as a result of angioplasty that failed without producing any complication. The remaining 13 cases were operated upon because complications occurred during angioplasty. These were coronary artery dissection in four, occlusion in five, continuing se...

Brief myocardial ischemia of less than 20 min duration, followed by reperfusion, is known to cause transient contractile dysfunction, often termed myocardial stunning. Tagged magnetic resonance imaging offers a noninvasive method that can be used to quantify this regional mechanical dysfunction in stunned myocardium. To this end, a closed-chest canine model of myocardial stunning was created by...

Left ventricular performance during percutaneous transluminal coronary angioplasty was assessed in 52 patients by intravenous digital subtraction ventriculography. After injection of contrast into the right atrium ventriculograms were obtained before and during balloon inflation. In 37 patients they were also obtained after the procedure. A 12 lead electrocardiogram was monitored throughout. Du...

BACKGROUND Glucose-insulin-potassium infusions are beneficial in uncomplicated patients with acute myocardial infarction (AMI) but are of unproven efficacy in AMI with left ventricular (LV) dysfunction because of volume requirements associated with glucose infusion. Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin with both insulinotropic and insulinomimetic properties that sti...

BACKGROUND Right ventricular dysfunction has been observed in uremic patients receiving percutaneous transluminal angioplasty (PTA). This prospective study focuses on the impact of tissue Doppler imaging echocardiographic parameters on assessing right ventricle function in uremic patients post PTA of dysfunctional hemodialysis access. METHODS Sixty uremic patients were divided into two groups...

BACKGROUND Exercise and rehabilitation are important methods for decreasing the risk factors of coronary artery disease (CAD). We aimed to evaluate the effect of the cardiac rehabilitation (CR) exercise program on the cardiac structure and physiology in patients undergoing percutaneous coronary intervention (PCI). METHODS In this randomized controlled study, 146 patients with CAD were divided...

OBJECTIVES This study aimed to explore the therapeutic efficacy of intensified walk training under the electrocardiogram (ECG) telemetry in stroke induced lower limb dysfunction patients with heart failure. MATERIAL AND METHODS A total of 40 patients with stroke induced lower limb dysfunction and heart failure were randomized into control group and walk training group (n=20 per group). Beside...