نتایج جستجو برای: angiotensinogen m235t polymorphism

تعداد نتایج: 109322  

Journal: :American journal of hypertension 2000
S Takami Y Imai T Katsuya T Ohkubo I Tsuji K Nagai H Satoh S Hisamichi J Higaki T Ogihara

The polymorphism of the angiotensin-converting enzyme gene is considered to be associated with increased risk for stroke, but there is a diversity in the results obtained. The genetic involvement of the renin-angiotensin system in stroke also remains unclear. To predict the genetic risk of lacunar infarction, we conducted an association study in an Ohasama population, which is the cohort in a r...

Journal: :Clinica chimica acta; international journal of clinical chemistry 2009
Kolandaswamy Anbazhagan Krishnaswamy Sampathkumar Muthiah Ramakrishnan Paneerselvam Gomathi Sivasamy Gomathi Govindan Sadasivam Selvam

BACKGROUND Several Renin Angiotensin System (RAS) polymorphisms alter the homeostasis to an abnormal state. Similarly, other genes such as Nephrin (NPHS1) and Podocin (NPHS2) contribute to the loss of renal function during renal diseases. In Indian population, studies in RAS and other renal specific gene polymorphisms in Chronic Kidney Disease (CKD) patients are scanty. METHODS We examined 11...

Journal: :Avicenna journal of medical biochemistry 2022

Background: Marker gene polymorphisms linked with the renin-angiotensin-aldosterone system (RAAS) have been broadly studied in diabetic nephropathy (DN) patients considering that RAAS is a potential drug target to slow down kidney disease progression. Objectives: The aim of present study was determine link between M235T and T174M variants angiotensinogen (AGT) DN. Methods: A total 93 DN, mean a...

Journal: :Hypertension 2006
Ilan Goldenberg Arthur J Moss Daniel Ryan Scott McNitt Shirley W Eberly Wojciech Zareba

The M235T mutation of the human angiotensinogen gene has been shown to be associated with elevated circulating angiotensinogen concentrations and essential hypertension. The frequencies of the 235T allele are significantly different in black and white subjects. We analyzed the independent contribution of the angiotensinogen M235T mutation to the development of recurrent coronary events (coronar...

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