1. N-Hydroxyacetamidoaryl compounds (hydroxamic acids) are metabolites of arylamides, and an enzyme that transfers the acetyl group from these derivatives to arylamines has been found in rat tissues. The reaction products were identified by thin-layer chromatography and a spectrophotometric method, with 4-amino-azobenzene as acetyl acceptor, was used to measure enzyme activity. 2. The acetyltra...

A two-stage "tandem strategy" for the regiocontrolled synthesis of very highly substituted quinolines is described. Benzannulation based on the reaction of cyclobutenones or diazo ketones with N-propargyl-substituted ynamides proceeds via a cascade of several pericyclic reactions to generate multiply substituted aniline derivatives. In the second stage of the tandem strategy, triflate derivativ...

Five malonanilide derivatives (M1-M5) were prepared by the reaction of ethyl malonate with aniline derivatives. These compounds were investigated as new stabilizers for double-base propellants (DBPs). The evaluation process has been performed through thermal stability tests, thermal analyses measurements (TGA and DSC) and kinetic parameters calculations (E(a)). The results of the new stabilizer...