This assessment of a genetically engineered (GE) salmon is the first evaluation of a GE animal and will set a precedent for future approvals of GE animals. FDA should be especially cognizant of the scientific quality of the data and the rigor of the analysis needed to do a proper safety assessment of GE animals in this case. Unfortunately, the evidence of FDA’s evaluation of the AquAdvantage sa...

In estrogen-dependent rat adrenocortical carcinomas, thymidine kinase activity decreased during tumor regression following removal of estrogen from the host. The change in the kinase activity could be prevented by estrogen administration but not by the administration of growth hormone or adrenocorticotropic hormone. The alterations in kinase activity were not due to changes in the activity of c...

Rhamdia quelen is an important Neotropical catfish species for fisheries and aquaculture in southern Brazil, where it is called Jandia. Like other native Brazilian species of economic importance, R. quelen genetics needs more attention for animal breeding programs. The growth hormone gene is known to be linked to a number of molecular markers and quantitative trait loci. We sequenced the coding...

Sutarno (2010) Genetic variations among Indonesian native cattle breeds based on polymorphisms analysis in the growth hormone loci and mitochondrial DNA. Biodiversitas 11: 1-5. Genetic variation within breeds is important and its study has become a subject of interest in livestock species, as it has many applications in animal breeding and genetics, such as the identification of animals and par...

In estrogen-dependent rat adrenocortical carcinomas, thymidine kinase activity decreased during tumor regression following removal of estrogen from the host. The change in the kinase activity could be prevented by estrogen administration but not by the administration of growth hormone or adrenocorticotropic hormone. The alterations in kinase activity were not due to changes in the activity of c...

background: the aim of this study was to evaluate the effect of local injection of human growth hormone (gh) in stimulating cartilage and bone formation in a rabbit model of temporomandibular joint (tmj). materials and methods: in an experimental animal study, 16 male albino new zealand white rabbits aged 12 weeks were divided into two groups: in the fi rst group (7 rabbits) 2 mg/kg/1 ml human ...

Objective: The aim of the present study was to evaluate the effect of growth hormone on growth parameters such as Z scores for height, weight, and body mass index (BMI), and height velocity in two groups of children with chronic renal failure (CRF) treated with and without growth hormone.Methods: This longitudinal study was conducted on all children aged 6 months to 16 years with a short ...

Sutarno (2010) Genetic variations among Indonesian native cattle breeds based on polymorphisms analysis in the growth hormone loci and mitochondrial DNA. Biodiversitas 11: 1-5. Genetic variation within breeds is important and its study has become a subject of interest in livestock species, as it has many applications in animal breeding and genetics, such as the identification of animals and par...

The remarkable progress in understanding the genetic basis of life-span determination in invertebrates indicates that impairments in the insulin-insulin-like growth factor 1 (IGF-1) signaling cascade increase longevity. Similarities among insulin and IGF-1-like signaling pathways in invertebrates and mammals raise the possibility that modifications of these pathways may extend life span in mamm...