Anthelmintic resistance is a major threat to current measures for helminth control in humans and animals. The introduction of anthelmintic vaccines, as a complement to or replacement for drug treatments, has been advocated as a preventive measure. Here, a computer-based simulation, tracking the dynamics of hosts, parasites and parasite-genes, shows that, depending on the degree of host-populati...

Evaluation of anthelmintic activity of any drug when carried out in laboratory conditions by using the isolated worms from nature cannot be adaptable with artificial laboratory conditions. Therefore, the present study aims at developing a new adaptable method for evaluation of anthelmintic activity. The present anthelmintic activity study reveals a new methodology with housefly worms cultured i...

Gisekia Pharnaceoides Linn is a diffuse subsucculent, glabrous herb. It is aromatic, aperient and act as powerful anthelmintic in cases of taenia. The plant possesses antibacterial, CNS depressant and anthelmintic activity. The present communication deals with the morphology, anatomy, microscopic constants, Physicochemical constants preliminary phytochemical studies and fluorescence Linn.

The anthelmintic activity of the Imethanolic extract of the root bark of Carissa carandas was evaluated on adult Indian earthworm (Pheretima posthuma) using albendazole as a reference standard. The extract caused paralysis followed by the death of worm at the tested dose level. The extract at the highest tested concentration has anthelmintic activity comparable with that of standard drug albend...

AIM To evaluate the efficacy and safety of the novel anthelmintic combination, derquantel-abamectin, against gastrointestinal nematode populations in sheep, under field-use conditions. METHODS Controlled faecal egg count reduction tests (FECRT) were conducted in New Zealand in 14 trials, covering a range of geographic locations, farming enterprises, breeds, nematode populations, and anthelmin...

We measured in vitro anthelmintic activity in extracts from 85 species of Australian native shrub, with a view to identifying species able to provide a degree of worm control in grazing systems. Approximately 40% of the species showed significant activity in inhibiting development of Haemonchus contortus larvae. The most active extracts showed IC50 values of 60-300 microg/ml. Pre-incubation wit...

Artocarpus lakoocha Roxb (Moraceae) is cultivated in Uttar Pradesh, Bengal, Khasi Hills and Western Ghats. Objectives of the present study were to determine antibacterial, antioxidant, anthelmintic and insecticidal efficacy of methanol extract of A. lakoocha fruit pericarp. Antibacterial activity was tested against by Agar well diffusion method. Antioxidant activity in terms of free radical sca...

Objective: Terminalia chebula gall extracts are widely used Asian folk and traditional medicine. The present study was carried out to evaluate the anthelmintic potential of different extracts of leaf galls. Materials and Methods: The anthelmintic activity was assessed by applying five different concentrations of the plant extracts on Indian adult earthworms, and the time of paralysis and death ...

objective: the present study was conducted to detect possible chemicals (phytoconstituents), prove ethno-medicinal value of the plant, and investigate antimicrobial, anthelmintic, and total phenolic content of crude methanolic extract of the solanum violaceum plant.  materials and methods: phytochemical screening was carried out using different chemical group test methods. in anthelmintic activ...

Novel benzimidazolo indane-1, 3-dione derivatives were synthesized and characterized by IR, HNMRand Mass spectral analysis. Biological screening of synthesized compounds allowed the identification of some novelanthelmintic agents bearing indane-1, 3-dione and benzimidazole scaffolds. Some of these compounds exhibited promisinganthelmintic activities.