hepatitis b virus (hbv) infection and its sequelae such as cirrhosis and hepatocellular carcinoma has remained a serious public health problem throughout the world. the who strategy for effective control of hbv infection and its complications is mass vaccination of neonates and children within the framework of expanded programme on immunization (epi). vaccination with hepatitis b surface antige...

OBJECTIVE The HLA 8.1 ancestral haplotype (HLA-B*08/DRB1*03/DQA1*05/DQB1*02) is associated with adult/juvenile idiopathic inflammatory myopathy (IIM), but confers a greater strength of association in patients possessing anti-Jo-1 or anti-PM-Scl antibodies. The HLA-DPB1 gene is centromeric to other HLA class II loci and separated by a recombination hotspot. We investigated whether HLA-DPB1 assoc...

In recent years, the utility of vascular complement factor 4d (C4d) deposition as diagnostic tool for antibody mediated rejection (AMR) after lung transplantation, has become a controversial issue. We aimed to pinpoint problematic nature C4d biomarker with simple experiment. quantified in broncho-alveolar lavage (BAL) transplant patients diverse post-transplant complications 3 different setting...

Objectives: To explore the expression of maternal serum IgG anti-A (B) and neonatal direct anti globulin, free antibody and Red Blood Cell (RBC) antibody on the occurrence and development of ABO Haemolytic Disease of the New-born (ABO-HDN) and provide a valuable reference for the early diagnosis of the disease. Methods: we selected 546 cases of jaundice and hyperbilirubinemia neonates in our ho...

BALB/c mice were immunized with the murine antihuman high-molecular-weight melanoma-associated antigen monoclonal antibodies (MoAbs) 149.53, 225.28, 653.25, and 763.74. Antiidiotypic antibodies could be detected in bleedings obtained 3 days following the first booster, increased in titer in bleedings obtained following the second booster, and persisted at high level in bleedings obtained 38 day...

introduction: measles is a severe contagious disease preventable by vaccination. besides the prevalence of measles in iran, ministry of health conducted a nation-wide vaccination against measles for all the 5-25 years old population in 2003. this study was done to evaluate the anti measles igg antibody among the medical students from baqiyatallah university of medical science. materials & metho...

Objective: Preventing communicable diseases in the armed forces (AF) of a country is considered as a national interest and has a great importance. There are limited data on the efficacy of vaccination of the navy personnel. This study was designed to evaluate both the safety and the immunogenicity of a recombinant hepatitis B (HB) vaccine made by Pasteur Institute of Iran (IPI-rHB), in this tar...