Abstract Background There is a decrease in vaccine-specific antibody to certain vaccine-preventable diseases in children after chemotherapy, but the frequency of non-immune patients is not clear. In the present case-control study, was taken under investigation protection level to Hepatitis B infection in children 6 months after completing chemotherapy. Materials and Methods In this study 6...

Conventional serum antibody titer, which expresses level, does not provide antigen binding avidity of the variable region antibody, is essential for defense response to infection. Here, we quantified anti-SARS-CoV-2 receptor-binding domain (RBD) by competitive binding-inhibition activity (IC50) between SARS-CoV-2 S1 immobilized on DCP microarray and various RBD doses added expressed as 1/IC50 n...

background: in iran, despite the use of vaccine since 1976, we are still having local epidemics especially in the children aged 15-20 years old. since 1996, the yearly epidemics of measles have been reported in these groups in sistan- baluchestan province, south east of iran. the present study was conducted to determinate the level of immunity in this target population in zahedan. methods: a to...

conclusions more than 95% of 15 to 25 year-old women (main reproductive age in iran) are within acceptable immunity range. level of immunity to rubella in women of reproductive age in this region appears satisfactory. patients and methods this descriptive cross-sectional study was conducted on 760 women younger than 25 years attending medical centers in ahvaz. a sample of 3 ml of venous blood w...

background: mycobacterium tuberculosis is a major cause of mortality and morbidity worldwide. infection with this bacterium is known to induce the development of autoantibodies of which a few are also known to be diagnostic markers for some other diseases. antineutrophil cytoplasmic antibodies (anca's) are among those autoantibodies used in clinical setting for diagnosing systemic vasculit...

Background: There is a controversy about the relation between anti-hepatitis B (anti-HBs) antibody level and obesity. We designed this study to compare the vaccine efficacy in obese/overweight and non-obese cases. Methods: In this cross-sectional study, 242 obese/overweight and 85 non-obese individuals were participated. Cases were selected from a referral clinic for obesity and a referral hepa...

development of a stool antigen immunoassay to detect helicobacter pylori infection requires monoclonal antibody against the specific antigen. alkylhydroperoxide reductase (ahpc) of helicobacter pylori has been described as a specific and unique enzyme for h. pylori and therefore, both h. pylori ahpc and anti-ahpc could be useful in the development of serologic and stool antigen tests, for detec...

background: anti-sperm antibody (asa) can decrease sperm motility and, therefore, it is a cause of male infertility. the aim of this study was to evaluate the effects of varicocelectomy on anti-sperm antibody in patients with varicocele. methods: this observational study was conducted on 90 patients with varicocele at sina and imam khomeini hospitals during 2006 to 2009. all varicocelectomy can...

there are various methods to diagnosis of hydatic cyst. serological methods based on tracing special antigens have high sensitivity, but the first need to design the kits based on serological methods is having enough amount of appropriate antibody against hydatic cyst antigens. hydatic cyst antigens and parasite protoscolexes prepared from sheep liver samples were injected to rabbits to obtain ...