Background: Epilepsy is a neurological disorder caused by uncontrollable discharge of action potentials from neurons in the brain. After seizure, oxidative stress may cause significant neuronal damage. In current study, we assessed anticonvulsant and antioxidant properties pioglitazone, peroxisome proliferated activated receptor-γ (PPAR-γ) agonist that used type-2 diabetes, on pilocarpine-induc...