Antidiabetic and antihyperlipidemic effect of Hemidesmus indicus Linn.R.root. (HIR) was investigated in rats. Administration of HIR (40 mg/g body weight/day) for four weeks significantly decreased the serum cholesterol, triglyceride, free fatty acids and phospholipid. Four weeks treatment of diabetic rats with HIR (40 mg/g body weight/day) showed significant hypoglycemic effect. Results of the ...

Aim: Many traditional treatments have been recommended in the alternative system of medicine for treatment of diabetes mellitus. Juglans regia is one of the medicinal plants used in traditional Iranian medicine as a treatment for diabetes, but little scientific documentation supports its antidiabetic action. Th e purpose of this study was to investigate antidiabetic eff ect of J. regia leaves i...

Aloe vera gel has been claimed to have antidiabetic activity but not all published results are consistent. We investigated the effect of oral administration of one tablespoonful of Aloe vera juice, twice a day for at least 2 weeks in patients with diabetes. Blood sugar and triglyceride levels in the treated group fell; cholesterol levels were not affected. The results suggest the potential of a...

Polyherbal extract which consists of ethanolic extract of MadhucaLatifolia, AristolochiaBracteata, AristolochiaIndica was investigated for its possible antidiabetic effect in alloxan-induced diabetic rats and to assess the synergistic activity of three plants. The animals were grouped into four six animals each. The first group received normal saline solution(0.9% sodium chloride), which was us...

Diabetes mellitus is the most common metabolic disorder affecting millions worldwide. It is recognized as a global major health problem. As alternatives to the available orthodox medicines, plants are considered a potential source for the treatment of diabetes within traditional ethnomedicine practices. In the Jordanian traditional medicine a significant selection of ethnobotanicals is promoted...

The thiazolidinedione class peroxisome proliferator-activated receptor gamma (PPARγ) agonists are restricted in clinical use as antidiabetic agents because of side effects such as edema, weight gain, and heart failure. The single and selective agonism of PPARγ is the main cause of these side effects. Multitargeted PPARα/γ/δ pan agonist development is the hot topic in the antidiabetic drug resea...

The aim of this research was to investigate antidiabetic activity of Costus igneus (also known as insulin plant) leaves extracts in streptozotocin induced diabetic albino rats. A comparison was made between the action of Costus igneus extract and a known antidiabetic drug glibenclamide (5mg/kg body wt.). An oral glucose tolerance test (OGTT) was also performed in experimental diabetic rats. Eth...

Memecylon malabaricum cogn (Melastomataceae) is an indigenous medicinal plant used in ethno medicine for the treatment of bacterial infections, inflammation and skin diseases including herpes, chickenpox. It’s also a root ecbolic. The methanolic extract of Memecylon malabaricum leaves is subjected to antidiabetic activity using experimental model of alloxan induced diabetes. The results showed ...