The first case of Alternaria infectoria ocular infection is reported. Keratitis and endophthalmitis developed after eye-perforating trauma from a lemon tree branch. Two months after surgery and empirical steroid and antibiotic treatment, diagnosis by molecular methods was performed. PCR amplification was positive for a fungus after 4 h. Antifungal treatment with amphotericin B and fluconazole w...

BACKGROUND Invasive fungal infections such as candidiasis and mold infections cause significant morbidity and mortality in seriously ill patients. Micafungin is an echinocandin antifungal agent with potent activity against most species of Candida and Aspergillus. We did this meta-analysis to clarify whether micafungin offers superior efficacy and safety compared with other antifungal agent for ...

Aegle marmelos has been used as antidiarrheal, antibacterial and antifungal agent in Unani system of medicine. The plant is highly used by the rural and tribal people for the treatment of diseases. However, despite its traditional usage as an antidiarrheal, antibacterial and antifungal agent, there is limited information regarding its uses in different diseases. The present article enumerates v...

Restricticin (1) is a naturally-occurring antifungal agent which contains triene, pyran and glycine ester functionalities and is unrelated to any previously known family of natural products. This unstable compound, as well as its corresponding N,N-dimethyl derivative (2), have been produced and isolated from both solid and liquid fermentations of Penicillium restrictum. The desglycyl hydrolysis...

Over the years, the different scientific societies have established a series of recommendations on antifungal prophylaxis based on prospective studies performed with different drugs1-6. Table 1 summarises these recommendations for the three situations in which fungal infection is most frequent: acute leukaemias, myelodysplastic syndromes and autologous and allogenic hematopoietic stem cell tran...

Effects of different carbon sources on growth and production of antifungal agent(s) by Gymnopilus spectabilis were investigated. Different carbon sources including; Glucose, fructose, lactose, maltose, manitol and sucrose at the concentration of 10 g/l and slow releasing carbon sources including malt extract and soluble starch at the concentration of 2g/l were used. Inhibition of spore germinat...