Polypharmacy, the use of multiple and potentially inappropriate medications, is an increasing problem among older adults. The global polypharmacy prevalence 34.6% in patients with COVID-19, COVID-19 increases age. present paper proposes that adults other comorbid conditions linked to medication outcome reporting bias randomized controlled trials. Outcome can occur when treatment efficacy report...

Tanshinone IIA is one of the active principles in danshen (Salvia miltiorrhiza Bge) widely used in treatment of cardiovascular disorders. We investigated the effect of danshen or tanshinone IIA on blood pressure and its possible mechanisms. An i.p. injection of danshen at 10 mg kg(-1) significantly lowered systolic blood pressure (SBP) of spontaneously hypertensive rats (SHRs) but failed to mod...

A hypertension crisis is an acute complication characterized by a severe increase in blood pressure, generally occurring ≥ 180/120 mmHg. Risk factors for occur due to history of disease the family, and age as that cannot be modified. An unhealthy lifestyle, including consuming alcohol, uncontrolled hypertension, or compliance taking antihypertension drugs, modifiable factor but often cause chro...

Abstract In Indonesia, Curculigo latifolia, popularly known as lemba, is used traditional medicine for antihypertension, antidiabetic, and a food drink additive. Despite the high benefits, this plant difficult to propagate due its low seed viability. Tissue culture offers an alternative propagation, thus providing continuous source of bioactive substances. The study aimed establish efficient me...

Sea cucumbers are amongst the highest value seafoods available commercially, especially in south-east Asian region, primarily due to their nutritional and health benefits as applied Traditional Chinese Medicine. While majority of studies for products derived from sea cucumber compounds have been conducted vitro , number vivo evidence-based human clinical limited. This review has critically asse...