background essential oils (eos) possess antibacterial properties and represent a natural source to treat infections and prevent food spoilage. their chemical composition might be affected by the environmental condition and the developmental growth stages of the plant. objectives the current study aimed to determine the variations in chemical compositions and antimicrobial activities of the eos ...

The antimicrobial peptide KLKLLLLLKLK-NH2 was developed based on sapesin B, and synthesized using D-amino acids. Biochemical properties of the D-form and L-form KLKLLLLLKLK-NH2 peptides were compared. In order to limit the effects due to bacterial resistance to proteolysis, antimicrobial activities of the peptides were evaluated after short-term exposure to bacteria. D-form KLKLLLLLKLK-NH2 exhi...

The present study was designated to evaluate the antimicrobial activities of various solvent extracts from fruits of Terminalia chebula. The preliminary antimicrobial activities of the extracts against cariogenic organisms were tested by using disc diffusion assay. The methanolic extract showed higher antimicrobial activity against all the cariogenic organisms tested. Based on this finding, the...

The effect of gamma and microwave irradiation on antioxidant and antimicrobial activities of Cinnamomum zeylanicum and Echinacea purpurea were investigated. In this study, all samples were exposed to gamma irradiation at doses 10, 15, 20 and 25 kGy and microwave irradiation at power of 100, 180 and 300 W for 5 min. In order to undergo the sequence expriments, the hydroalcoholic (EtOH 50%) extra...

Peptides that exert antimicrobial activity in artificial media may lack activity within blood or other complex biological matrices. To facilitate the evaluation of antimicrobial peptides for possible therapeutic utility, an ex vivo assay was developed to assess the extent and durability of peptide antimicrobial activities in complex fluid biomatrices of whole blood, plasma, and serum compared w...

abstract: essential oils are commonly used to treat minor health problems. in this study the chemical compositions of lavandula officinalis and thymus vulgaris were determined by gas chromatography and mass spectrometry. gc/ms analysis of t. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of l. officinalis. the antibacter...

Drugs from natural sources are used for treating various diseases since the ancient times. From the literature it is clear that various type of pharmacological and biological activities are associated with Azadirachta indica. The leave oil of A. indica is known to have good antimicrobial potential. The oil of A. indica leaves, was tested against the different infectious microorganisms [Gram pos...

The antimicrobial effects of diethanolamine, dimethylamino-methyl-propanol, and butylethanolamine are greatly enhanced at high pH. Their antimicrobial activities are closely correlated with their uncharged forms, indicating that diffusion through cell membrane(s) is rate limiting for the antimicrobial action. Since these compounds are selectively toxic at high pH, they are appropriate antimicro...

Eighteen novel 5-phenyl-3-(substitutedthioxoquinazolinonyl) isoxazoles (5a-r) were synthesized by cycloaddition of various chalcones with hydroxylaminehydrochloride (NH2OH.HCl). All the newly synthesized compounds were confirmed by their spectral and analytical data. They were evaluated for antimicrobial, antihelminthic, analgesic and anti-inflammatory activities with an objective to evaluate t...