introduction: amnesia or loss of memory is the cardinal hallmark of alzheimer’s disease (ad), a progressive neurodegenerative disorder associated with ageing process. although, ad had been discovered over a century ago, drugs which could cure or halt the progression of the disease are yet to see the light of the day. however, there has been a growing interest in the use of phytomedicines with m...

conclusions according to the obtained data, synthesized pyridine based chalcones (3a-3j) could be proposed as potential antioxidant lead compounds. background natural chalcones and also their synthetic derivatives have attracted increasing attention due to various pharmacological applications. development and discovery of new chalcones with antioxidant activities is one of the attracting areas ...

in this work, quantitative structure-property relationship (qspr) approaches were used to predict the redox potential of 42 phenolic antioxidants. the structures of all compounds optimized by the am1 semi-empirical method and then a large number of molecular descriptors were calculated for each compound in the data set. subsequently, stepwise multilinear regression was applied to select the mos...

Carcinogens are involved in carcinogenesis, mutagenesis and genotoxicity. One of the best ways to minimize the detrimental effects of carcinogens is by the use of medicinal plants i.e., natural anticarcinogens. Naturally occurring anticarcinogenic principles present in medicinal plants, human diet have protective effects against carcinogens. These include flavonoids, phenolics, coumarins, carot...

The present study was designed to evaluate and compare the phenolic (total phenols and flavonoid) contents and antioxidant activity of aqueous extract of Momordica foetida (AEMF) and ethanolic extract of Momordica foetida (EEMF) extract of Momordica foetida leaves; a popular medicinal plant used for traditional medicine preparations. The antioxidant activity of both extracts was assessed using ...

The heartwood of Caesalpinia sappan L. (Caesalpiniaceae) is traditionally used in China and Ayurveda. In Thailand it is used as coloring agent in beverage, food, garment and cosmetics. The objective of this study is to find out which ages of wood giving effective natural antioxidant. The heartwood extracts in various ratio of extraction solution CH3OH:CH2Cl2 and various ages were measured for t...

Coffee is a rich source of dietary antioxidants, and this property, coupled with the fact that coffee is one of the world's most popular beverages, has led to the understanding that coffee is a major contributor to dietary antioxidant intake. Brewed coffee is a complex food matrix with numerous phytochemical components that have antioxidant activity capable of scavenging free radicals, donating...

The objective of the present study was to evaluate the antioxidant activity, antitumor effect, and antiaging property of proanthocyanidins from Kunlun Chrysanthemum flowers (PKCF) grown in Xinjiang. In vitro antioxidant experiments results showed that the total antioxidant activity and the scavenging capacity of hydroxyl radicals ((•)OH) and 1,1-diphenyl-2-picrylhydrazyl (DPPH(•)) radicals incr...

The popularity of fruit tea is increasing in the world because of its antioxidant properties and attractive taste. The aim of this study was to determine and compare the antioxidant property and phenolic composition of 16 different fruit teas. The antioxidant property and total phenol content of fruit teas depending on the extraction condition (water temperature) were examined using the ABTS (2...

BACKGROUND Sesame oil is a potent antioxidant dietary source for human health. Oxidative stress through generation of free radicals damages the myocardium in different experimental condition. The present research was designed to evaluate the antioxidant property of chronic oral administration of sesame oil against isoproterenol induced myocardial injury. METHODS AND RESULTS Male Wistar albino...