نتایج جستجو برای: antiproliferation
تعداد نتایج: 403 فیلتر نتایج به سال:
BACKGROUND This study aims to determine the synergistic effects of the chemotherapeutic drug melphalan and the phytoconstituents extracted from Pinus kesiya Royle ex Gordon (Simaosong) in human cancer cells. METHODS P. kesiya twigs extracted from 50 % ethanol-water were evaluated alone (6-500 µg/mL) and in combination with melphalan (0.75-15 µg/mL). The cytotoxic effects of single extract or ...
The Anti-proliferative Ability of the Ethanol Extract of Annona muricata Leaves on Widr Cancer Cells
Soursop (Annona muricata) leaves are widely distributed in the tropics, including Indonesia. known to contain many anticancer compounds. Research from various countries using soursop provides a different picture of size dose. This research is qualitative determine antiproliferative properties leaf alcohol extract on Widr cells as model colon cancer cells. The were provided Medicinal Plant and T...
OBJECTIVES To investigate the anticancer activities of Chinese motherwort herb (Leonurus heterophyllus Sweet; LHS). DESIGN Dried LHS was extracted and reconstituted in phosphate-buffered saline. The in vitro antiproliferation activities of the extract were tested against seven human cancer cell lines. The DNA ladder assay and cell morphologic studies were performed to verify the drug's apopto...
PURPOSE We aimed to assess the biologic activity of PF-03084014 in breast xenograft models. The biomarkers for mechanism and patient stratification were also explored. EXPERIMENTAL DESIGN The in vitro and in vivo properties of PF-03084014 were investigated. The mRNA expressions of 40 key Notch pathway genes at baseline or after treatment were analyzed to link with the antitumor efficacy of PF...
Purpose: We aimed to assess the biologic activity of PF-03084014 in breast xenograft models. The biomarkers for mechanism and patient stratification were also explored. Experimental Design: The in vitro and in vivo properties of PF-03084014 were investigated. The mRNA expressions of 40 key Notch pathway genes at baseline or after treatment were analyzed to link with the antitumor efficacy of PF...
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