Editorial Sexual dysfunction is a common side effect of psychotropic drugs and has received much attention because of its negative effects on quality of life and adherence to antidepressant agents. In patients with depression, sexual dysfunction can be attributed to the underlying disorder or to antidepressant drugs. Sexual dysfunction also can occur with first generation antipsychotic drugs an...

The use of neuroleptics in the elderly has been a topic of debate since 2005 when the US Food and Drug Administration issued a black-box warning of increased risk of mortality in elderly patients with dementia-related psychosis. Antipsychotic alternatives such as divalproex are sometimes favored on an "off-label" basis to manage agitation in the demented elderly, and antipsychotic use is often ...

The advent of novel antipsychotic medications has raised treatment expectations for patients with severe mental illness. In this regard, clozapine has been particularly effective in reducing aggressive behavior in patients with schizophrenia. This study compared the efficacy of risperidone and conventional antipsychotic medications in the management of hostile patients. Improvements in the leve...

OBJECTIVE Long-acting antipsychotic agents were developed to promote treatment compliance in patients requiring maintenance treatment for schizophrenia. METHOD An analysis of the impact of non-compliance on treatment outcomes in schizophrenia and the advantages and disadvantages of long-acting antipsychotics. RESULTS Partial or total non-compliance with oral antipsychotics remains widesprea...

Abstract There are a lot of studies investigating gender differences in the side effects first and second-generation antipsychotic drugs. Even though some seen at higher rates women, it is not determined yet influence on efficacy agents still well clear. In this review, we give brief overview leading probably to distinguished clinical outcomes both sexes. Disclosure Interest None Declared

Recent developments in psychopharmacology have lead to the introduction of several novel antipsychotic agents into clinical practice. As these agents become more commonly encountered, it is essential that forensic psychiatrists have a working knowledge of their efficacy as well as the advantages of their use. This article reviews current literature regarding the clinical efficacy and mechanisms...

Drug debates normally proceed without scrutiny of why the particular issues being debated are considered the crucial issues. One plausible influence on the terms of debates is the interest groups involved. Four drug debates are addressed in this paper: neuroleptics, drugs in sport, analgesics and marijuana. The key interest groups and their likely influence on the terms of debates are examined....