نتایج جستجو برای: antivenom

تعداد نتایج: 906  

2011
Himmatrao Saluba Bawaskar Pramodini Himmatrao Bawaskar

OBJECTIVE Envenomation by Mesobuthus tamulus scorpion sting can result in serious cardiovascular effects. Scorpion antivenom is a specific treatment for scorpion sting. Evidence for the benefit of scorpion antivenom and its efficacy compared with that of commonly used vasodilators, such as prazosin, is scarce. We assessed the efficacy of prazosin combined with scorpion antivenom, compared with ...

Journal: :Australian Prescriber 2012

Journal: :The Medical journal of Australia 2010
Andrew Churchman Margaret A O'Leary Nicholas A Buckley Colin B Page Alan Tankel Chris Gavaghan Anna Holdgate Simon G A Brown Geoffrey K Isbister

OBJECTIVE To describe the clinical features and laboratory findings in patients with definite red-bellied black snake (RBBS; Pseudechis porphyriacus) bites, including correlation with results of venom assays. DESIGN, PATIENTS AND SETTING Prospective cohort study of patients with definite RBBS bites, recruited to the Australian Snakebite Project from January 2002 to June 2010. MAIN OUTCOME M...

2017
Emilie Alirol Sanjib Kumar Sharma Anup Ghimire Antoine Poncet Christophe Combescure Chabilal Thapa Vijaya Prasad Paudel Kalidas Adhikary Walter Robert Taylor David Warrell Ulrich Kuch François Chappuis

BACKGROUND Currently, there is inadequate evidence on which to base clinical management of neurotoxic snakebite envenoming, especially in the choice of initial antivenom dosage. This randomised controlled trial compared the effectiveness and safety of high versus low initial antivenom dosage in victims of neurotoxic envenoming. METHODOLOGY/ PRINCIPAL FINDINGS This was a balanced, randomised, ...

Journal: :Journal of the South African Veterinary Association 2004
A L Leisewitz R S Blaylock F Kettner A Goodhead A Goddard J P Schoeman

Cases of snakebite envenomation are frequently presented to veterinary practitioners in southern Africa. Despite this, no published guidelines exist on how this medical emergency should be managed. Southern African snake venoms can be classified into 3 main types based on the main mechanism of venom action and clinical presentation. A polyvalent antivenom is manufactured in South Africa and con...

2014
Steven Fernandez Wayne Hodgson Janeyuth Chaisakul Rachelle Kornhauser Nicki Konstantakopoulos Alexander Ian Smith Sanjaya Kuruppu

This study investigated the in vitro toxic effects of Bitis arietans venom and the ability of antivenom produced by the South African Institute of Medical Research (SAIMR) to neutralize these effects. The venom (50 µg/mL) reduced nerve-mediated twitches of the chick biventer muscle to 19% ± 2% of initial magnitude (n = 4) within 2 h. This inhibitory effect of the venom was significantly attenua...

Journal: :The New England journal of medicine 2009
Leslie V Boyer Andreas A Theodorou Robert A Berg Joanne Mallie Ariana Chávez-Méndez Walter García-Ubbelohde Stephen Hardiman Alejandro Alagón

BACKGROUND Clinically significant scorpion envenomation by Centruroides sculpturatus produces a dramatic neuromotor syndrome and respiratory insufficiency that often necessitate intensive supportive care. We hypothesized that a scorpion-specific F(ab')(2) antivenom would promptly resolve clinical symptoms in children with this syndrome. METHODS In a randomized, double-blind study, the efficac...

Journal: :South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2009
Darryl Wood Caroline Webb Jenine DeMeyer

OBJECTIVE We aimed to study the outcomes of severe snakebites in patients admitted to Ngwelezana Hospital in north-eastern KwaZulu-Natal, the seasonal variations, and the effectiveness and complications of antivenom. DESIGN A prospective observational outcomes study was conducted over one year (1 June 2007 to 31 May 2008). The study group was from the north-eastern KwaZulu-Natal region of Sou...

Background: Immunotherapy is the only specific treatment for scorpion envenomation. In the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (BUN and creatinine) induced by Mesobuthus eupeus (Me) scorpion venom was investigated in anesthetized rabbits. Methods: Twenty four rabbits were randomized into four gro...

Journal: :British medical journal 1980
D A Warrell M J Warrell W Edgar C R Prentice J Mathison

Bites and envenoming by the carpet viper Echis carinatus are common medical emergencies in parts of Nigeria, but the most effective use of the various commercially produced antivenoms in treatment has not been established. Pasteur Paris Echis monospecific and Behringwerke West and North Africa Bitis-Echis-Naja polyspecific antivenoms were compared in two groups of seven patients with incoagulab...

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