OBJECTIVE Anxious depression is a distinct clinical subtype of major depressive disorder (MDD) characterized by palpitations, somatic complaints, altered interoceptive awareness, high risk of suicide, and poor response to pharmacotherapy. However, the neural mechanisms of anxious depression are still not well understood. In this study we investigated changes in neural oscillation during the res...

Theory and treatment for childhood anxiety disorders typically implicates children's negative cognitions, yet little is known about the characteristics of thinking styles of clinically anxious children. In particular, it is unclear whether differences in thinking styles between children with anxiety disorders and non-anxious children vary as a function of child age, whether particular cognitive...

Delivering and receiving a postnatal diagnosis of Down syndrome is not an easy experience for most physicians or parents. In this study, 467 mothers of children with Down syndrome in Spain completed a survey about the postnatal support services they received immediately following the diagnosis of their child. Mothers reported feeling anxious, frightened, guilty, angry, and, in rare cases, suici...

BACKGROUND The association between life events and anxious depression might be due to causality or to gene-environment correlation. We examined unidirectional and reciprocal causality and a gene-environment correlation model, in which genes that influence the vulnerability for anxious depression also increase the risk of exposure to life events. The effect of genes that influence environmental ...

UNLABELLED Anxious depression, defined as major depressive disorder (MDD) accompanied by high levels of anxiety, seems to be difficult to treat with traditional antidepressant monotherapy. The purpose of this study was to assess the efficacy of ziprasidone monotherapy in patients with anxious depression versus non-anxious depression. One hundred and twenty outpatients were enrolled in a 12-week...

Adolescence is accompanied by specific biological, cognitive, and identity changes. A decreased level of tolerance and identity anxieties are among the signs that can emerge during this period and affect students’ mental health and their quality of academic life. This study aimed to determine the effect of mindfulness based on cognitive-behavioral therapy focusing on anger management regarding ...

Ninety-two subjects solved a series of problems without enough time to finish and worked either at a pace and in an order determined by the experimenter (experimenter-paced) or at their own pace and order under self-administered time deadlines (self-paced). Self-pacing resulted in superior performance on rote and poorer performance on cognitive problems relative to experimenter-paced groups. Se...

Visiting an inner-city prison as a medical student, I was unsure how I would respond to this mass incarceration of life. The anxiety manifesting in my stomach as I passed through the entrance gate, the fear of how inmates would respond to me and of names they might call. Corridors were cold, stark, echoic, with a constant reminder of inmates’ plight to end their lives in the endless safety nett...