INTRODUCTION The predisposition, infection, response and organ dysfunction (PIRO) staging system was designed as a stratification tool to deal with the inherent heterogeneity of septic patients. The present study was conducted to assess the performance of PIRO in predicting multiple organ dysfunction (MOD), intensive care unit (ICU) admission, and 28-day mortality in septic patients in the emer...

Methods. Prospectively collected data from all patients admitted to a German university hospital postoperative ICU between August 2004 and December 2005 were analysed. The probability of ICU mortality was calculated for SAPS II, APACHE II, adjusted APACHE II (adj-APACHE II), SAPS 3, and SAPS 3 customized for Europe [C-SAPS3 (Eu)] using standard formulas. To improve calibration of the prognostic...

OBJECTIVE To examine the accuracy of the existing data collection system in an intensive care unit (ICU). METHODS Prospective audit of data collection for APACHE II in a six-bedded general ICU in a region-al hospital for consecutive ICU admissions over a 12 month period. The existing resident medical officer (RMO) data collection system continued unaltered while concurrent collection of APACH...

BACKGROUND This study examines the efficacy of the predicting power for need for mechanical ventilation and duration of mechanical ventilation of three different scoring systems in a medical-surgical intensive care unit. METHODS One-hundred eighty critically ill patients were included prospectively in our study in a consecutive period of seven months. On the day of admission, data were collec...

Disease-related malnutrition of neurocritical illness harms its treatment, which increases the mortality rate. The aim of this study was evaluating the effect of a high protein diet on the dietary factors, clinical outcome, and mortality rate of neurocritical patients. In a randomized controlled trial, 15 neurocritical patients were recruited in each group. Patients in the intervention and cont...

INTRODUCTION Using physiologic scoring systems for identifying high-risk patients for mortality has been considered recently. This study was designed to evaluate the values of Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiologic Score (SAPS II) models in prediction of 1-month mortality of critically ill patients. METHODS The present prospective cross ...

INTRODUCTION The performance of N-terminal pro-brain natriuretic peptide (NT-proBNP) and C-reactive protein (CRP) to predict clinical outcomes in ICU patients is unimpressive. We aimed to assess the prognostic value of NT-proBNP, CRP or the combination of both in unselected medical ICU patients. METHODS A total of 576 consecutive patients were screened for eligibility and followed up during t...

Purpose Urosepsis implies clinically evident severe infection of urinary tract with features of systemic inflammatory response syndrome (SIRS). We validate the role of a single Acute Physiology and Chronic Health Evaluation II (APACHE II) score at 24 hours after admission in predicting mortality in urosepsis. Materials and Methods A prospective observational study was done in 178 patients adm...