Time is money", or so goes the old saying. Perhaps influenced by this aphorism, some strategies for incorporating costs in the analysis of software design express all costs in currency units for reasons of simplicity and tractability. Indeed, in theoretical economics all costs can, in principle, be expressed in dollars. Software engineering problems, however, often present situations in which c...

I read with interest Mark Wilson's recent article, "The New England Journal of Medicine: commercial conflict of interest and revisiting the Vioxx scandal". I believe this is an important contribution that underlines the aphorism "Those who don't know history are doomed to repeat it." As Vioxx is a seminal example, it is important to place it in its proper context, examining if this malfeasance ...

Objective: Supported in the Hippocratic aphorism primum non nocere, the bioethical principle of non-maleficence pray that the medical act cause the least damage or injury to the health of the patient, leaving it to the doctor to assess the risks of a particular therapy through knowledge of possible adverse events of drugs. Among these, the rebound effect represents a common side effect to numer...

Research on "Society and GIS" has fallen into a trap to the extent that it separates these two realms. As an antidote to rampant technological determinism, this paper demonstrates how the highly technical decisions inside GIS software have a distinctly social flavor, in particular they specify a division of labor (and thus of knowledge). In the case of map registration, the software adopts an o...

DOI: 10.4103/0975-9476.96514 “Healthy Aging” was the theme of World Health Day this year. This should be a decadal research mission for Ayurveda. Advancements in agriculture, science, technology, and biomedicine have increased human life expectancy, while the same have also contributed to the fall in the birth rates. As a result, for the fi rst time in human history we will soon have more geria...

The aphorism “All models are wrong but some are useful” (Box, 1978) sums up much of what ML is about. The assumptions we make in the Naive Bayes approach to sentimanet classification are wrong, but this is true of the assumptions made in all current formal models of human language (statistical or otherwise), with the possible exception of a few which are very restricted indeed. However, the que...

"Change or die!" Is the title and opening concept of Alan Deutschman's article for Fast Company magazine. As aphorism indicates, change is crucial if an enterprise wants to remain invincible in market competition. Therefore, we investigate study several academic sources relating innovation. After analyzing different economic innovation models problems confronted by innovation, believe that alth...

Dion, Berscheid, and Walster (1972), in their seminal article, labeled the attribution of positive characteristics to attractive people the "beauty-is-good" stereotype. The stereotyping literature since then provides extensive evidence for the differential judgment and treatment of attractive versus unattractive people, but does not indicate whether it is an advantage to be attractive or a disa...

The relations between dentofacial orthopedics and occlusodontics are an on-going subject of interest for practitionersofbothdisciplines.Thenumerous publications, including several previous special issues of the Revue d’ODF/ Journal of Dentofacial Anomalies and Orthodontics, that have been devoted to this topic over the last thirty years bear ample testimony to its importance. Temporomandibular ...

The aphorism was to develop new chemical entities as potential anticancer, anti-inflammatory, and analgesic agents. The Leuckart synthetic pathway was utilized in development of novel series of 2-(substituted phenoxy)-N-(1-phenylethyl)acetamide derivatives. The compounds containing 1-phenylethylamine as basic moiety attached to substituted phenols were assessed for their anticancer activity aga...