Background: This study aimed to investigate the possible apoptotic role of bortezomib (BMZ) on pancreatic islets streptozotocin (STZ)-induced diabetic rats.

Abstract Background Colorectal cancer (CRC), with a growing incidence trend worldwide, is resistant to apoptosis and has uncontrolled proliferation. It recently reported that probiotic microorganisms exert anticancer effects. The genus Bifidobacterium , one of the dominant bacterial populations in gastrointestinal tract, received increasing attention because widespread interest using it as heal...

Alzheimer's disease (AD) is the most common form of dementia. Due to multifaceted nature AD pathology and limited understanding its etiology, difficult be treated with currently available pharmaceuticals. Recent studies suggest that transplantation mesenchymal stem cells might have therapeutic potential on several neurodegenerative disorders. In addition, it can ameliorate neuropathological def...

Panax ginseng is known to potentiate the immune system via its antioxidant properties. Cadmium as an environmental pollutant has destructive effects on body organs especially reproductive system. This study investigated of P. extract against cadmium-induced testicular toxicity in rats. In this experimental study, 50 male adult rats were randomly divided into 5 groups: A significant decrease was...

Baculoviruses, like their holometabolous host insects, comprise a monophyletic clade and, since the evolutionary origin of this virus family, have coevolved with hosts. Despite intimate coevolutionary relationship, baculoviruses occasionally diverged independently phylogeny by acquiring new infection mechanisms. Given that current baculovirus genomes contain various anti-apoptotic genes and pse...

The influence of heat shock proteins (HSPs) on protein quality control systems in cardiomyocytes is currently under investigation. effect HSPs the regulated cell death (CMCs) great importance, since they play a major role implementation compensatory and adaptive mechanisms event cardiac damage. mediate number that activate apoptotic cascade, playing both pro‑ anti‑apoptotic roles depending thei...

Evaluation of Apoptotic Effect Protein Fusion, Enterocin A, R-Type Pyocin, Lactocin, and Specific Ligand on Gastric Cancer Cell Line (AGS)