The ECOR collection of natural Escherichia coli isolates was screened to determine the proportion of strains that carried functional, cryptic and nonfunctional genes for utilization of the three beta-glucoside sugars, arbutin, salicin and cellobiose. None of the 71 natural isolates utilized any of the beta-glucosides. Each strain was subjected to selection for utilization of each of the sugars....

While the medicinal fungus Inonotus obliquus produces polyphenols as one of its main metabolites in natural habitats, it accumulates less polyphenols under laboratory conditions. In this study we found that the continuous addition of 1 mM H(2)O(2) at a rate of 1.6 ml/h into a submerged culture of the fungus enhanced its production of mycelia, melanins, flavonoids and hispidin analogs (HA). Simu...

Background: Medical use of ionizing radiation has direct/indirect undesirable effects on normal tissues. In this study, the radioprotective effect of arbutin in megavoltage therapeutic x-irradiated mice was investigated using serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), and asparate amniotransferase (AST) activity measurements. Material and Methods: In this analytical...

Objective: Arbutin has been shown to have antioxidant and free-radical scavenging properties. The aim of this study was to investigate the effects of arbutin administration on behavioral impairment, and oxidative and nitrosative stress in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced animal model of Parkinson’s disease (PD). Materials and Methods: PD model was developed by 4 int...

freckles and pigmented acne scars, are of serious concern to women. Their treatment usually involves the use of medicines or medicinal cosmetics containing depigmenting agents or skin-whitening agents. For example, hydroquinone and 4methoxyphenol are used as topical therapies for hyperpigmentation disorders. Active ingredients available for medicated whitening cosmetics in Japan include vitamin...

Specific plant signal molecules are known to induce syringomycin production and expression of syrB1, a syringomycin synthetase gene, in Pseudomonas syringae pv. syringae. This report demonstrates that syringopeptin production likewise is activated by plant signal molecules and that the GacS, SalA, and SyrF regulatory pathway mediates transmission of plant signal molecules to the syr-syp biosynt...

Arbutin và axit kojic được biết đến là chất ức chế tyrosinase thường sử dụng trong mỹ phẩm sản làm trắng da. Tuy nhiên, gây ra nhạy cảm da, khi arbutin có khả năng độc tế bào. Do đó, việc tìm nguồn gốc thiên nhiên đang rất quan tâm. Nghiên cứu này nhằm đánh giá tác động enzyme của các cao chiết từ lá nho Vitis vinifera L.. Cao toàn phần bằng phương pháp ngâm với chloroform, cồn 96o nước. Tác th...