As the human immunodeficiency virus and sexually transmitted disease epidemics advance relentlessly, it is clear that an armamentarium of therapeutic and preventive methods will be essential to their containment. Topical microbicides--self-administered prophylactic agents applied to the vagina or rectum in various formulations--could be a crucial addition to that necessary armamentarium. This a...

The implementation and execution of effective infection control protocols among all health care communities cannot be overstressed. Infection control becomes even more significant in dentistry as more microorganisms are found in the oral cavity than in any about half as infectious as blood, and the most likely modes of transmission in dental offices are through puncture wounds, skin abrasions, ...

Dronedarone is a derivative of amiodarone with similar mechanisms of action (blocking calcium, potassium and sodium channels in addition to having anti-adrenergic effects). Compared to amiodarone it has fewer drug interactions (though it can interact with all current anticoagulants), more limited risk of organ toxicity, a much shorter half-life with no need for a loading regimen, but lower effi...