In this study leucocyte ascorbic acid concentrations and plasma ascorbic acid levels were measured simultaneously and correlation between these two variables was sought in various bacterial and viral infections. A total of 258 patients were studied. The control group consisted of 21 healthy children in the same age group. Except for scarlet fever no significant differences were observed between...

The availability of L-ascorbic acid labeled with Cl4 had made possible studies on the metabolism of the vitamin in man (l), guinea pig (2,3), and rat (4, 5). In the present investigation the metabolic fate of carboxyllabeled n-ascorbic acid and carboxyl-labeled L-ascorbic acid was compared in guinea pigs and rats. This study is of interest, since little is known of the biological fate of D-asco...

introduction: after presbycusis, noise-induced hearing loss is the second most common cause of acquired hearing loss. numerous studies have shown that high-intensity noise exposure increases free radical species; therefore, use of antioxidants to detoxify the free radicals can prevent cellular damage in the cochlea. we studied the potential hearing protective effect of different doses of ascorb...

introduction: ascorbic acid is a water-soluble vitamin solved in water that acts as a helper of some the enzymes in the reactions of energy metabolism. thus, the study aims to investigate the use of supplemental ascorbic acid on the aerobic and anaerobic capacity of the children.methodology: participants of this quasi-experimental study were 18 children in esfahan who were randomly selected and...

In vitro studies have demonstrated pro-oxidant effect of ascorbic acid on sheep erythrocyte hemolysate and on purified ruminant hemoglobin preparations. Methemoglobin formation was concentration dependent over ca. 3.4 through 34 μmole ascorbic acid with sheep hemolysate (r=0.97, p<0.01, n= 3 each) and over ca. 5.68 through 22.7 μmole ascorbic acid with purified ruminant Hb preparations (r >0.99...

After an acute myocardial infarction, there is an apparent acute fall in leucocyte ascorbic acid associated with an acute rise in white blood cells and serum cortisol. The apparent fall in leucocyte ascorbic acid is the result of the granulocytosis which occurs after the infarction. Estimations of ascorbic acid disclose that the granulocyte contains approximately half the ascorbic acid of the l...

Ascorbic acid (vitamin C) was found in isolated human mononuclear leukocytes and their purified components in millimolar concentration. Intracellular ascorbic acid was depleted greater than 96% during cell culture and was rapidly reaccumulated after addition of physiologic concentrations of ascorbic acid to the extracellular medium. Purified cells maintained concentration gradients of ascorbic ...