ASE spiral for ROIs within five different cortical regions, where the SNR in each region is normalized to the SNR obtained using ASE spiral (summed using SS). The three ROIs on the right are located in SFG regions. None differ significantly. Figure 1: Z-shim ASE Triple Spiral sequence, showing acquisition of up to 3 spiral images per excitation with z-shim gradient before each acquisition. Z-sh...

In this cooperative study, we explored the role of the carbohydrate moiety (CHO) of von Willebrand factor (vWF) in supporting platelet adhesion. Because of previous discrepant results, all purification steps and CHO modifications by various enzymes were critically evaluated. Under our conditions, CHO-modified vWF preparations contained less than 5% of the initial sialic acid ([Neu]-ase-vWF) and...

Many models of local species interactions predict the occurrence of priority effects due to alternative stable equilibria (ASE). However, few empirical examples of ASE have been shown. One possible explanation for the disparity is that local ASE are difficult to maintain regionally in patch dynamic models. Here we examine two possible mechanisms for regional coexistence of species engaged in lo...

IntroductIon The presence of polychlorinated biphenyls (PCBs) in fish and other marine organisms is of immediate environmental and regulatory concern. To determine the concentrations of PCBs indicative of contaminant exposure, and lipids, which also characterize physiological conditions of fish, the analytes must first be extracted. Traditionally, this has been done using Soxhlet methods that a...

Functional left/right asymmetry ("laterality") is a fundamental feature of many nervous systems, but only very few molecular correlates to functional laterality are known. At least two classes of chemosensory neurons in the nematode Caenorhabditis elegans are functionally lateralized. The gustatory neurons ASE left (ASEL) and ASE right (ASER) are two bilaterally symmetric neurons that sense dis...

In colorectal cancer (CRC), an inherited susceptibility risk affects about 35% of patients, whereas high-penetrance germline mutations account for <6% of cases. A considerable proportion of sporadic tumors could be explained by the coinheritance of multiple low-penetrance variants, some of which are common. We assessed the susceptibility to CRC conferred by genetic variants at the TGFBR1 locus....

The relationship between returns, volatility and trading volume has interested financial economists and analysts for a number of years. A widely documented result is the positive contemporaneous relationship between price returns and trading volume. This paper investigates the contemporaneous and dynamic relationships between trading volume, returns and volatility for Greek index futures (FTSE/...

This study was carried out to assess the radioprotective effect of Alstonia scholaris against gamma irradiation in mice. Adult Swiss albino mice were exposed to different doses of gamma radiation in the presence (experimental) or absence (control) of Alstonia scholaris extract (ASE). Dose tolerance of ASE, DRF, CFU colonies in spleen, LPx and GSH were studied. The optimum dose for radioprotecti...

RNA-seq technology enables large-scale studies of allele-specific expression (ASE), or the expression difference between maternal and paternal alleles. Here, we study ASE in animals for which parental RNAseq data are available. While most methods for determining ASE rely on read alignment, read alignment either leads to reference bias or requires knowledge of genomic variants in each parental s...