perinatal asphyxia using the cardiac biomarkers cTnI and brain natriuretic peptide (BNP). Troponin T and I are sensitive markers of myocardial injury following a perinatal hypoxic-ischaemia insult. BNP is a marker of ventricular wall stress secondary to myocardial dysfunction [8] . cTnI and BNP were collected before the start of hypothermia, at 24 and 48 h after birth, and after rewarming. BNP ...

BACKGROUND Traumatic asphyxia is probably much more common than the surgical literature shows and should always be kept in mind as a possible complication of injuries of the chest and abdomen. AIMS Traumatic asphyxia or Perte's syndrome results from a severe crush injury causing sudden compression of the thorax. During a 3-year period, we treated five cases of traumatic asphyxia, which we rep...

INTRODUCTION Perinatal asphyxia is one of the main causes of perinatal mortality and morbidity worldwide and it generates high costs for health systems; however, it has modifiable risk factors. OBJECTIVE To identify the risk factors associated with the development of perinatal asphyxia in newborns at Hospital Universitario del Valle, Cali, Colombia. MATERIALS AND METHODS Incident cases and ...

OBJECTIVE To determine risk factors for perinatal asphyxia. DESIGN Cohort study. SETTING Teaching hospital. METHODS All consecutive hospital births were evaluated during the study period. Asphyxia was defined on intrapartum and neonatal resuscitation criteria. Maternal, intrapartum and neonatal variables were recorded in all births. Data was analyzed after stratifying for live and stillbi...

BACKGROUND Asphyxia is a medical condition in which placental or pulmonary gas exchange is impaired or they cease all together, typically producing a combination of progressive hypoxemia and hypercapnea. OBJECTIVE In addition to regional differences in its etiology; it is important to know its risk factors. MATERIALS AND METHODS This is a case-control study, all neonates born from May 2002 ...

INTRODUCTION Crush asphyxia is different from positional asphyxia, as respiratory compromise in the latter is caused by splinting of the chest and/or diaphragm, thus preventing normal chest expansion. There are only a few cases or small case series of crush asphyxia in the literature, reporting usually poor outcomes. CASE PRESENTATION We present the case of a 44-year-old Caucasian man who dev...

BACKGROUND Perinatal asphyxia can cause serious illness or death. By taking steps in the «latent phase», which occurs 6-24 hours after the hypoxic event, the neurological damage caused by perinatal asphyxia can be limited. We wish to present a selection of such measures that are either established treatment today or that appear promising. METHOD We searched in the Medline and Cochrane Library...

Birth asphyxia is often associated with a high seizure burden that is predictive of poor neurodevelopmental outcome. The mechanisms underlying birth asphyxia seizures are unknown. Using an animal model of birth asphyxia based on 6-day-old rat pups, we have recently shown that the seizure burden is linked to an increase in brain extracellular pH that consists of the recovery from the asphyxia-in...

Perinatal asphyxia induces retinal lesions, generating ischemic proliferative retinopathy, which may result in blindness. Previously, we showed that the nitrergic system was involved in the physiopathology of perinatal asphyxia. Here we analyze the application of methylene blue, a well-known soluble guanylate cyclase inhibitor, as a therapeutic strategy to prevent retinopathy. Male rats (n = 28...