This study describes the experiences of four groups of healthcare providers who facilitate exercise interventions for people with multiple sclerosis (MS)-related fatigue. Fatigue is a complex symptom frequently experienced by people with MS, yet it is poorly understood by clinicians and clinical researchers. Historically, clinicians have recommended less physical activity in order to limit fati...

Attention is important in error processing. Few studies have examined the link between sustained attention and error processing. In this study, we examined how error-related negativity (ERN) of a four-choice reaction time task was reduced in the mental fatigue condition and investigated the role of sustained attention in error processing. Forty-one recruited participants were divided into two g...

Mental rotation task (MRT) incorporates elements of spatial abilities, important in many professions, with people of both genders involved. Importantly, these are the areas where spatial tasks might be performed for long time periods; thus adverse effects of mental fatigue are highly unwanted. Substantial variation of MRT performance in relation to estrogen levels has been observed in many stud...

Research on partially automated driving has revealed relevant problems with driving performance, particularly when drivers' intervention is required (e.g., take-over when automation fails). Mental fatigue has commonly been proposed to explain these effects after prolonged automated drives. However, performance problems have also been reported after just a few minutes of automated driving, indic...

This study proposes a system that uses virtual reality to create the illusion of decreased training load through cross-modal effects, which are when two senses, such as sight and hearing, interact influence one another. The utilizes head-mounted display headphones for auditory visual sensory presentation while participants engage in squatting exercises. We use chair adjusts seat elevation preve...

Detecting rare and surprising events is a useful strategy for sensory -systems. In the human auditory system, deviance detection is indexed by an important component of the auditory event-related potentials, the mismatch negativity (MMN). Responses of single neurons in the inferior colliculus, medial geniculate body, and auditory cortex of mammals (cats, rats, and mice) show responses that shar...

Chronic Fatigue Syndrome (CFS) or Myalgic Encephalomyelitis (ME) is a debilitating disorder, affecting at least 250,000 people in the UK. Marked by debilitating fatigue, its aetiology is poorly understood and diagnosis controversial. A number of symptoms overlap with other illnesses with the result that CFS/ME is commonly misdiagnosed. It is important therefore that significant clinical feature...

Introduction In October, 1957, the Medical Staff of the Royal Free Hospital reported in the British Medical Journal an outbreak of an illness amongst the hospital staff in 1955. Between 13 July of that year and 24 November, 292 members of the medical, nursing, auxiliary medical, ancillary, and administrative staff were affected by the illness and, of these, 255 patients were admitted to hospita...