Autologous peripheral blood stem cell transplantation (auto-PBSCT) after high dose chemotherapy is usually offered to breast cancer patients carrying a high risk of relapse or having chemosensitive metastatic disease. Whether progression free and overall survival of such patients is improved after auto-PBSCT compared to conventional chemotherapy is a matter of debate. Currently available result...

To study whether regional injection of recombinant interleukin 2 (rIL-2) can induce an in vivo lymphocyte activation in cervical lymph nodes (LNs) of patients with head and neck carcinoma, 12 patients, candidates for prophylactic dissection, were treated for 7-10 days prior to surgery with rIL-2, 10(5) units/day, injected in the perimastoid region. A marked induction of cytotoxic activity again...

Enhanced Green Fluorescent Protein (eGFP) shows much stronger fluorescence than its ancestor, (GFP), thus has been widely applied as a reporter for biomedical research. In this study, we reported the expression of synthetic codon optimized gene encoding eGFP in Escherichia coli (E. coli). The was cloned into two vectors, pQE30 and pColdII resulting recombinant vectors were transformed E. M15 BL...

objective: this study was conducted with the aim to investigate and compare iranian produced and foreign oxytocin for use in induction of labor. materials and methods: this random clinical trial was conducted on a population of 198 pregnant women with live fetus and cephalic presentation and conditions conducive to induction of labor, monitored by obstetricians and gynecologists. they were rand...

Despite the critical role of the Langerhans cells in the induction of contact hypersensitivity reactions, non-Langerhans antigen-presenting cells in already sensitized individuals may play a role in the elicitation phase of a contact hypersensitivity reaction. Following epicutaneous challenge with antigens, the number of CD1+DR+ epidermal Langerhans cells increased in a time-dependent way and, ...

To investigate the auto-induction of cytochrome P450 (CYP450) by Chloroxoquinoline (CXL), a novel anticancer drug. Three experiments related to the induction of CYP450 were performed: a) In vitro use of the rat fresh hepatocytes model; b) In vivo 'cocktail' of CYP450 probe model; c) Pharmacokinetic (PK) study of the single and multiple doses. Some typical CYP enzyme probes and inducers were use...

Induction motor is widely used in small scale as well as the large scale industries. In industrial sector, there prevails a major drawback in speed controlling of three phase induction motor drives when subjected to heavy loads. These are called as disturbances in a motor. A motor can have both the internal disturbance as well as the external disturbance. To eliminate this types of disturbance ...

The incidences of schistosomiasis and multiple sclerosis (MS) are mutually exclusive worldwide suggesting that schistosomiasis may offer protection against the induction of the immune-mediated disease, MS. Recent studies using the mouse model of MS, experimental autoimmune encephalomyelitis, support a direct suppression of the onset of MS by chronic Schistosoma mansoni infection. Self-reactive ...

Chattering is undesirable phenomenon when dealing with sliding mode control. This paper proposed a new method for addressing chattering with a simple and easy implementation in Digital Signal Processor (DSP). This is realized by replacing the discontinuous function in conventional sliding mode control with statedependent auto-tuning of boundary layer in fast sigmoid function and state-dependent...