introduction worldwide, chronic liver disease is a major cause of morbidity and mortality. causes of elevated serum alanine aminotransferase (alt) levels vary depending on the population under study. the aim of this study is to evaluate the frequency and causes of persistently elevated alt levels in patients of the gastroenterology (gi) clinics in ghaem and emam reza hospitals in mashhad, iran....

INTRODUCTION Chronic hepatitis is a liver disease in the form of continuous inflammation and necrosis for at least 6 months. There are many causes of chronic hepatitis, including genetic disorders, drugs, toxins, autoimmune, idiopathic; but the most common cause is viral. The virus that causes chronic viral hepatitis is the hepatitis B virus (HBV), hepatitis C virus (HCV), as well as hepatitis ...

A family is described in which there occurred two cases of the lupoid type of active chronic hepatitis with cirrhosis, one of chronic persistent hepatitis, and one of myasthenia gravis. The two cases of lupoid hepatitis were in the proposita, a schoolgirl aged 16 years, and her great-aunt aged 69 years whom she had never met. The case of myasthenia gravis was that of the father. The whole famil...

Patients 100 patients (mean age 40 y, 62% men) who had increased aminotransferase concentrations for >6 months, serum antibodies to HCV found by polymerase chain reaction (PCR), and a diagnosis of chronic hepatitis on a liver biopsy sample in the previous 12 months. Exclusion criteria included previous treatment with interferon á-2b or ribavirin, decompensated cirrhosis, autoimmune hepatitis, c...

Autoimmune hepatitis (AIH) is a chronic inflammatory process occurring in the hepatocytes, predominantly affecting females. We report an unusual presentation of AIH 28-year-old woman who was admitted with upper abdominal pain, vomiting, and fever for two weeks duration. Her imaging studies revealed multiple lesions liver suggestive infarctions. Laboratory investigations anaemia, thrombocytopeni...

OBJECTIVE To review the clinical spectrum and etiology of chronic liver disease in children at National Institute of Child Health, Karachi. METHODS Prospective study in children aged 1 to 14 years with suspected chronic liver disease. Complete blood count, LFT's, prothrombin time, serum albumin and ultrasound of abdomen were done in all patients. Liver biopsy was done in majority of the cases...