Intradermal injection of autologous serum and plasma elicit a cutaneous reactivity in almost 45-60% of patients with Chronic Idiopathic Urticaria (CIU). This reactivity is associated with the presence of auto antibodies against IgE or IgE receptors. This study was carried out to compare the cutaneous reactivity of autologous serum and plasma skin tests in a series of patients with CIU for diagn...

AIMS To evaluate umbilical cord serum therapy as a means of promoting the healing of persistent corneal epithelial defects. METHODS Umbilical cord serum or autologous serum drops were used to promote the healing of persistent epithelial defects. The study design was a prospective randomised controlled clinical trial. 60 eyes of 59 patients were divided into two groups, 31 in the cord serum gr...

Background and purpose Autologous conditioned serum (ACS) is a disease-modifying drug for treatment of osteoarthritis (OA). To establish that the autologous serum has protective effect on chondropathy. The aim of this study was evaluate the efficacy of ACS as osteoarthritis therapy. Methods Literature review for intraarticular ACS somministration in human study. Results and interpretation We an...

CASE REPORT We present two case reports of patients suffering from severe corneal damage resulting in pain and visual impairment, after undergoing Scopinaro's operation. Both patients improved after treatment with topical autologous serum although their nutritional state became worse. DISCUSSION Topical autologous serum provides growth factors and nutrients needed for corneal cell repair, and...

Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide bene...