نتایج جستجو برای: avermectin h2b1b
تعداد نتایج: 247 فیلتر نتایج به سال:
Most microbial secondary metabolites are producec as complexes of closely related compoundsby theii producing organisms. The avermectins1*, milbemycins2 and nemadectins3~5) are typical examples produced ii such a manner. The milbemyciif complex is known t( consist of more than twenty components6 ~ 8), however only a few are commercial products. A rationale for thii phenomenon may be related to ...
Ivermectin (MK-0933, 22, 23-dihydroderivative of amvermectin B1) is a synthetic derivative of a broadspectrum antiparasitic class of macro cyclic lactones known as avermectins. Avermectin B was first isolated by fermentation of a soil microorganism, the actinomycete Streptomyces avermitilis. Ivermectin has a structure similar to that of macrolide antibiotics, but without antibacterial activity ...
Ivermectin has potent systemic activity against numerous species of nematodes and arthropods, but there are some important species in these two groups, such as the cat flea, Ctenocephalides felis (Bouché), that appear to be refractory to it. In an effort to determine if the lack of systemic activity against C. felis is specific to ivermectin, or if it is a class-wide phenomenon, 20 avermectin d...
Competitive interactions between species can be mitigated or even reversed in the presence of anthropogenic influences. The thrips species Frankliniella occidentalis and Thrips tabaci are highly invasive and damaging agricultural pests throughout the world. Where the species co-occur, one species tends to eventually predominate over the other. Avermectin and beta-cypermethrin are commonly used ...
Glutamate-gated chloride channels (GluCl) are targets for avermectin/milbemycin (A/M) anthelmintics such as ivermectin that cause paralysis of somatic and pharyngeal muscles in gastrointestinal nematodes. Ivermectin is useful for onchocerciasis control programs because of its activity against microfilariae that often cause ocular disease and severe dermatitis. However, mechanisms responsible fo...
The avermectin analog doramectin (CHC-B1), sold commercially as Dectomax, is biosynthesized by Streptomyces avermitilis. aveC, a gene encoding an unknown mechanistic function, plays an essential role in the production of doramectin (avermectin CHC-B1), modulating the production ratio of CHC-B1 to other avermectins, most notably the undesirable analog CHC-B2. To improve the production ratio for ...
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